ALA‐A2 Is a Novel Anticancer Peptide Inspired by Alpha‐Lactalbumin: A Discovery from a Computational Peptide Library, In Silico Anticancer Peptide Screening and In Vitro Experimental Validation

ALA‐A2 Is a Novel Anticancer Peptide Inspired by Alpha‐Lactalbumin: A Discovery from a Computational Peptide Library, In Silico Anticancer Peptide Screening and In Vitro Experimental Validation

Abstract Anticancer peptides (ACPs) are rising as a new strategy for cancer therapy. However, traditional laboratory screening to find and identify novel ACPs from hundreds to thousands of peptides is costly and time consuming. Here, a sequential procedure is applied to identify candidate ACPs from...

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Bibliographic Details
Main Authors: Tassanee Lerksuthirat, Pasinee On‐yam, Sermsiri Chitphuk, Wasana Stitchantrakul, David S. Newburg, Ardythe L. Morrow, Suradej Hongeng, Wararat Chiangjong, Somchai Chutipongtanate
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Global Challenges
Subjects:
anticancer peptides
cytotoxic screening
drug discovery
lung adenocarcinoma
machine learning
peptide library
Online Access:https://doi.org/10.1002/gch2.202200213

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