Illuminating the complete ß-cell mass of the human pancreas- signifying a new view on the islets of Langerhans
Abstract Pancreatic islets of Langerhans play a pivotal role in regulating blood glucose homeostasis, but critical information regarding their mass, distribution and composition is lacking within a whole organ context. Here, we apply a 3D imaging pipeline to generate a complete account of the insuli...
Main Authors: | Joakim Lehrstrand, Wayne I. L. Davies, Max Hahn, Olle Korsgren, Tomas Alanentalo, Ulf Ahlgren |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-47686-7 |
Similar Items
-
Pig pancreas oxygenation at 20 degrees C increases islet ATP generation but deteriorates islet function.
by: Iken, M, et al.
Published: (2009) -
Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islets and islets isolated from normal and hDAF transgenic pigs.
by: Bennet, W, et al.
Published: (2001) -
Isolation of adult porcine islets of Langerhans.
by: Toso, C, et al.
Published: (2000) -
Transplantation or islets of Langerhans: new developments
by: A Caulfield, et al.
Published: (2001-12-01) -
Angiogenic capacity of endothelial cells in islets of Langerhans.
by: Linn, T, et al.
Published: (2003)