Biological Effects and Biomedical Applications of Areca Nut and Its Extract
The dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-02-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/17/2/228 |
_version_ | 1827342961259577344 |
---|---|
author | Ting Tong Aiqing Xu Shuhua Tan Hengzhi Jiang Lixin Liu Senwen Deng Haihua Wang |
author_facet | Ting Tong Aiqing Xu Shuhua Tan Hengzhi Jiang Lixin Liu Senwen Deng Haihua Wang |
author_sort | Ting Tong |
collection | DOAJ |
description | The dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to address various health issues, such as diarrhea, arthritis, dyspepsia, malaria, and so on. In this review, we have conducted a comprehensive summary of the biological effects and biomedical applications of AN and its extracts. Initially, we provided an overview of the constituents in AN extract. Subsequently, we summarized the biological effects of AN and its extracts on the digestive system, nervous system, and circulatory system. And we elucidated the contributions of AN and its extracts in antidepressant, anti-inflammatory, antioxidant, and antibacterial applications. Finally, we have discussed the challenges and future perspectives regarding the utilization of AN and its extracts as emerging pharmaceuticals or valuable adjuncts within the pharmaceutical field. |
first_indexed | 2024-03-07T22:17:35Z |
format | Article |
id | doaj.art-18b6d4dc59c043f79bd2b1d8f322150d |
institution | Directory Open Access Journal |
issn | 1424-8247 |
language | English |
last_indexed | 2024-03-07T22:17:35Z |
publishDate | 2024-02-01 |
publisher | MDPI AG |
record_format | Article |
series | Pharmaceuticals |
spelling | doaj.art-18b6d4dc59c043f79bd2b1d8f322150d2024-02-23T15:30:45ZengMDPI AGPharmaceuticals1424-82472024-02-0117222810.3390/ph17020228Biological Effects and Biomedical Applications of Areca Nut and Its ExtractTing Tong0Aiqing Xu1Shuhua Tan2Hengzhi Jiang3Lixin Liu4Senwen Deng5Haihua Wang6Hunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaThe dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to address various health issues, such as diarrhea, arthritis, dyspepsia, malaria, and so on. In this review, we have conducted a comprehensive summary of the biological effects and biomedical applications of AN and its extracts. Initially, we provided an overview of the constituents in AN extract. Subsequently, we summarized the biological effects of AN and its extracts on the digestive system, nervous system, and circulatory system. And we elucidated the contributions of AN and its extracts in antidepressant, anti-inflammatory, antioxidant, and antibacterial applications. Finally, we have discussed the challenges and future perspectives regarding the utilization of AN and its extracts as emerging pharmaceuticals or valuable adjuncts within the pharmaceutical field.https://www.mdpi.com/1424-8247/17/2/228areca nutbetel nutanti-inflammatory activityantioxidant activityantibacterial activityantidepressant activity |
spellingShingle | Ting Tong Aiqing Xu Shuhua Tan Hengzhi Jiang Lixin Liu Senwen Deng Haihua Wang Biological Effects and Biomedical Applications of Areca Nut and Its Extract Pharmaceuticals areca nut betel nut anti-inflammatory activity antioxidant activity antibacterial activity antidepressant activity |
title | Biological Effects and Biomedical Applications of Areca Nut and Its Extract |
title_full | Biological Effects and Biomedical Applications of Areca Nut and Its Extract |
title_fullStr | Biological Effects and Biomedical Applications of Areca Nut and Its Extract |
title_full_unstemmed | Biological Effects and Biomedical Applications of Areca Nut and Its Extract |
title_short | Biological Effects and Biomedical Applications of Areca Nut and Its Extract |
title_sort | biological effects and biomedical applications of areca nut and its extract |
topic | areca nut betel nut anti-inflammatory activity antioxidant activity antibacterial activity antidepressant activity |
url | https://www.mdpi.com/1424-8247/17/2/228 |
work_keys_str_mv | AT tingtong biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT aiqingxu biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT shuhuatan biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT hengzhijiang biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT lixinliu biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT senwendeng biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract AT haihuawang biologicaleffectsandbiomedicalapplicationsofarecanutanditsextract |