Biological Effects and Biomedical Applications of Areca Nut and Its Extract

The dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to...

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Main Authors: Ting Tong, Aiqing Xu, Shuhua Tan, Hengzhi Jiang, Lixin Liu, Senwen Deng, Haihua Wang
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/17/2/228
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author Ting Tong
Aiqing Xu
Shuhua Tan
Hengzhi Jiang
Lixin Liu
Senwen Deng
Haihua Wang
author_facet Ting Tong
Aiqing Xu
Shuhua Tan
Hengzhi Jiang
Lixin Liu
Senwen Deng
Haihua Wang
author_sort Ting Tong
collection DOAJ
description The dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to address various health issues, such as diarrhea, arthritis, dyspepsia, malaria, and so on. In this review, we have conducted a comprehensive summary of the biological effects and biomedical applications of AN and its extracts. Initially, we provided an overview of the constituents in AN extract. Subsequently, we summarized the biological effects of AN and its extracts on the digestive system, nervous system, and circulatory system. And we elucidated the contributions of AN and its extracts in antidepressant, anti-inflammatory, antioxidant, and antibacterial applications. Finally, we have discussed the challenges and future perspectives regarding the utilization of AN and its extracts as emerging pharmaceuticals or valuable adjuncts within the pharmaceutical field.
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spelling doaj.art-18b6d4dc59c043f79bd2b1d8f322150d2024-02-23T15:30:45ZengMDPI AGPharmaceuticals1424-82472024-02-0117222810.3390/ph17020228Biological Effects and Biomedical Applications of Areca Nut and Its ExtractTing Tong0Aiqing Xu1Shuhua Tan2Hengzhi Jiang3Lixin Liu4Senwen Deng5Haihua Wang6Hunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaHunan Key Laboratory of Economic Crops Genetic Improvement and Integrated Utilization, Hunan Binglang Science Institute, School of Life and Health Sciences, Hunan University of Science and Technology, Xiangtan 411201, ChinaThe dried, mature fruit of the palm tree species <i>Areca catechu</i> L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to address various health issues, such as diarrhea, arthritis, dyspepsia, malaria, and so on. In this review, we have conducted a comprehensive summary of the biological effects and biomedical applications of AN and its extracts. Initially, we provided an overview of the constituents in AN extract. Subsequently, we summarized the biological effects of AN and its extracts on the digestive system, nervous system, and circulatory system. And we elucidated the contributions of AN and its extracts in antidepressant, anti-inflammatory, antioxidant, and antibacterial applications. Finally, we have discussed the challenges and future perspectives regarding the utilization of AN and its extracts as emerging pharmaceuticals or valuable adjuncts within the pharmaceutical field.https://www.mdpi.com/1424-8247/17/2/228areca nutbetel nutanti-inflammatory activityantioxidant activityantibacterial activityantidepressant activity
spellingShingle Ting Tong
Aiqing Xu
Shuhua Tan
Hengzhi Jiang
Lixin Liu
Senwen Deng
Haihua Wang
Biological Effects and Biomedical Applications of Areca Nut and Its Extract
Pharmaceuticals
areca nut
betel nut
anti-inflammatory activity
antioxidant activity
antibacterial activity
antidepressant activity
title Biological Effects and Biomedical Applications of Areca Nut and Its Extract
title_full Biological Effects and Biomedical Applications of Areca Nut and Its Extract
title_fullStr Biological Effects and Biomedical Applications of Areca Nut and Its Extract
title_full_unstemmed Biological Effects and Biomedical Applications of Areca Nut and Its Extract
title_short Biological Effects and Biomedical Applications of Areca Nut and Its Extract
title_sort biological effects and biomedical applications of areca nut and its extract
topic areca nut
betel nut
anti-inflammatory activity
antioxidant activity
antibacterial activity
antidepressant activity
url https://www.mdpi.com/1424-8247/17/2/228
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