A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment

Carbon quantum dots (CQDs) are an emerging class of carbon-based nanomaterials. CQDs are receiving considerable interest in biomedical applications due to their low toxicity, stability profile, efficient surface tailorability, aqueous solubility, diverse functionality, biocompatibility, and size-tun...

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Main Authors: Kondi Soumya, Namdev More, Mounika Choppadandi, D.A. Aishwarya, Gajendar Singh, Govinda Kapusetti
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-12-01
Series:Biomedical Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949723X23000053
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author Kondi Soumya
Namdev More
Mounika Choppadandi
D.A. Aishwarya
Gajendar Singh
Govinda Kapusetti
author_facet Kondi Soumya
Namdev More
Mounika Choppadandi
D.A. Aishwarya
Gajendar Singh
Govinda Kapusetti
author_sort Kondi Soumya
collection DOAJ
description Carbon quantum dots (CQDs) are an emerging class of carbon-based nanomaterials. CQDs are receiving considerable interest in biomedical applications due to their low toxicity, stability profile, efficient surface tailorability, aqueous solubility, diverse functionality, biocompatibility, and size-tunable emission when compared to other conventional carbon quantum dots (CDs) of group II, III, IV & V. Improved photodynamic treatment, photosensitization, bioimaging, targeted drug delivery, fluorescent marker for disease-detection, cell tracking, and biosensors are made possible by the presence of diverse functional groups on the surface of CQDs, such as thiol, carboxyl, hydroxyl, etc. This article gives thorough understanding of CQDs for drug delivery applications by describing their origin and rationale. In addition, the in-vivo characteristics of CQDs are also examined in an initiative to strengthen the argument for CQDs as powerful drug delivery vehicles.
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spelling doaj.art-18b6e10e19744e7d98cb533ff40f9a6a2023-11-11T04:28:51ZengKeAi Communications Co., Ltd.Biomedical Technology2949-723X2023-12-0141120A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatmentKondi Soumya0Namdev More1Mounika Choppadandi2D.A. Aishwarya3Gajendar Singh4Govinda Kapusetti5Department of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaDepartment of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaDepartment of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaDepartment of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaDepartment of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaCorresponding author.; Department of Medical Devices, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gujarat, 380054, IndiaCarbon quantum dots (CQDs) are an emerging class of carbon-based nanomaterials. CQDs are receiving considerable interest in biomedical applications due to their low toxicity, stability profile, efficient surface tailorability, aqueous solubility, diverse functionality, biocompatibility, and size-tunable emission when compared to other conventional carbon quantum dots (CDs) of group II, III, IV & V. Improved photodynamic treatment, photosensitization, bioimaging, targeted drug delivery, fluorescent marker for disease-detection, cell tracking, and biosensors are made possible by the presence of diverse functional groups on the surface of CQDs, such as thiol, carboxyl, hydroxyl, etc. This article gives thorough understanding of CQDs for drug delivery applications by describing their origin and rationale. In addition, the in-vivo characteristics of CQDs are also examined in an initiative to strengthen the argument for CQDs as powerful drug delivery vehicles.http://www.sciencedirect.com/science/article/pii/S2949723X23000053Carbon quantum dotsPhotosensitizationBiomedical applicationsPhotodynamic therapyDrug delivery
spellingShingle Kondi Soumya
Namdev More
Mounika Choppadandi
D.A. Aishwarya
Gajendar Singh
Govinda Kapusetti
A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
Biomedical Technology
Carbon quantum dots
Photosensitization
Biomedical applications
Photodynamic therapy
Drug delivery
title A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
title_full A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
title_fullStr A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
title_full_unstemmed A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
title_short A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
title_sort comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment
topic Carbon quantum dots
Photosensitization
Biomedical applications
Photodynamic therapy
Drug delivery
url http://www.sciencedirect.com/science/article/pii/S2949723X23000053
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