Acute Kidney Injury is Associated with Lowered Plasma-Free Thiol Levels

Acute Kidney Injury is Associated with Lowered Plasma-Free Thiol Levels

Acute kidney injury (AKI) is associated with the abrupt loss of kidney function. Oxidative stress plays an important role in the pathophysiology of AKI. Free thiols (R-SH) are crucial components of the extracellular antioxidant machinery and reliably reflect systemic oxidative stress. Lower levels o...

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Bibliographic Details
Main Authors: Lisanne Boekhoud, Jacqueline Koeze, Elisabeth C. van der Slikke, Arno R. Bourgonje, Jill Moser, Jan G. Zijlstra, Anneke C. Muller Kobold, Marian L. C. Bulthuis, Matijs van Meurs, Harry van Goor, Hjalmar R. Bouma
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
sepsis
acute kidney injury (AKI)
reactive oxygen species (ROS)
oxidative stress
free thiols
hydrogen sulphide
Online Access:https://www.mdpi.com/2076-3921/9/11/1135

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