Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer
Key points Composition of the microbiome can influence patients response to immunotherapy Response to immunotherapy of NSCLC patients is associated with the presence of Akkermansiaceae in the gut Akkermansia could be used as a predictor for patient treated with immunological checkpoint inhibitors
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2022-07-01
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| Series: | AMB Express |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13568-022-01428-4 |
| _version_ | 1811323499534352384 |
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| author | Anna Grenda Ewelina Iwan Izabela Chmielewska Paweł Krawczyk Aleksandra Giza Arkadiusz Bomba Małgorzata Frąk Anna Rolska Michał Szczyrek Robert Kieszko Tomasz Kucharczyk Bożena Jarosz Dariusz Wasyl Janusz Milanowski |
| author_facet | Anna Grenda Ewelina Iwan Izabela Chmielewska Paweł Krawczyk Aleksandra Giza Arkadiusz Bomba Małgorzata Frąk Anna Rolska Michał Szczyrek Robert Kieszko Tomasz Kucharczyk Bożena Jarosz Dariusz Wasyl Janusz Milanowski |
| author_sort | Anna Grenda |
| collection | DOAJ |
| description | Key points Composition of the microbiome can influence patients response to immunotherapy Response to immunotherapy of NSCLC patients is associated with the presence of Akkermansiaceae in the gut Akkermansia could be used as a predictor for patient treated with immunological checkpoint inhibitors |
| first_indexed | 2024-04-13T13:56:15Z |
| format | Article |
| id | doaj.art-18beb8b224e645819cdd58155b18d256 |
| institution | Directory Open Access Journal |
| issn | 2191-0855 |
| language | English |
| last_indexed | 2024-04-13T13:56:15Z |
| publishDate | 2022-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | AMB Express |
| spelling | doaj.art-18beb8b224e645819cdd58155b18d2562022-12-22T02:44:10ZengSpringerOpenAMB Express2191-08552022-07-011211710.1186/s13568-022-01428-4Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancerAnna Grenda0Ewelina Iwan1Izabela Chmielewska2Paweł Krawczyk3Aleksandra Giza4Arkadiusz Bomba5Małgorzata Frąk6Anna Rolska7Michał Szczyrek8Robert Kieszko9Tomasz Kucharczyk10Bożena Jarosz11Dariusz Wasyl12Janusz Milanowski13Department of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Omics Analyses, National Veterinary Research InstituteDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Omics Analyses, National Veterinary Research InstituteDepartment of Omics Analyses, National Veterinary Research InstituteDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinChair and Department of Neurosurgery and Pediatric Neurosurgery, Medical University of LublinDepartment of Omics Analyses, National Veterinary Research InstituteDepartment of Pneumonology, Oncology and Allergology, Medical University of LublinKey points Composition of the microbiome can influence patients response to immunotherapy Response to immunotherapy of NSCLC patients is associated with the presence of Akkermansiaceae in the gut Akkermansia could be used as a predictor for patient treated with immunological checkpoint inhibitorshttps://doi.org/10.1186/s13568-022-01428-4AkkermansiaceaeNSCLCResponse to immunotherapyPD-1PD-L1Microbiome |
| spellingShingle | Anna Grenda Ewelina Iwan Izabela Chmielewska Paweł Krawczyk Aleksandra Giza Arkadiusz Bomba Małgorzata Frąk Anna Rolska Michał Szczyrek Robert Kieszko Tomasz Kucharczyk Bożena Jarosz Dariusz Wasyl Janusz Milanowski Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer AMB Express Akkermansiaceae NSCLC Response to immunotherapy PD-1 PD-L1 Microbiome |
| title | Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer |
| title_full | Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer |
| title_fullStr | Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer |
| title_full_unstemmed | Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer |
| title_short | Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer |
| title_sort | presence of akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non small cell lung cancer |
| topic | Akkermansiaceae NSCLC Response to immunotherapy PD-1 PD-L1 Microbiome |
| url | https://doi.org/10.1186/s13568-022-01428-4 |
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