Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer

Presence of Akkermansiaceae in gut microbiome and immunotherapy effectiveness in patients with advanced non-small cell lung cancer

Key points Composition of the microbiome can influence patients response to immunotherapy Response to immunotherapy of NSCLC patients is associated with the presence of Akkermansiaceae in the gut Akkermansia could be used as a predictor for patient treated with immunological checkpoint inhibitors

Bibliographic Details
Main Authors: Anna Grenda, Ewelina Iwan, Izabela Chmielewska, Paweł Krawczyk, Aleksandra Giza, Arkadiusz Bomba, Małgorzata Frąk, Anna Rolska, Michał Szczyrek, Robert Kieszko, Tomasz Kucharczyk, Bożena Jarosz, Dariusz Wasyl, Janusz Milanowski
Format: Article
Language:English
Published: SpringerOpen 2022-07-01
Series:AMB Express
Subjects:
Akkermansiaceae
NSCLC
Response to immunotherapy
PD-1
PD-L1
Microbiome
Online Access:https://doi.org/10.1186/s13568-022-01428-4

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