Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction
Virote Chalieopanyarwong, Worapat Attawettayanon Division of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, ThailandCorrespondence: Worapat AttawettayanonDivision of Urology, Department of Surgery, Faculty of Medicine, Songklana...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-09-01
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| Series: | Research and Reports in Urology |
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| Online Access: | https://www.dovepress.com/renal-cortical-thickness-after-pyeloplasty-in-pediatric-ureteropelvic--peer-reviewed-fulltext-article-RRU |
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| author | Chalieopanyarwong V Attawettayanon W |
| author_facet | Chalieopanyarwong V Attawettayanon W |
| author_sort | Chalieopanyarwong V |
| collection | DOAJ |
| description | Virote Chalieopanyarwong, Worapat Attawettayanon Division of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, ThailandCorrespondence: Worapat AttawettayanonDivision of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, 90110, ThailandTel +667-445-1428Email aworapat@medicine.psu.ac.thPurpose: The main goal of pyeloplasty is to maintain or improve renal function. Diuretic renography is the gold standard for evaluating renal function after pyeloplasty. Renal ultrasonography (RUS) is commonly used to determine hydronephrosis in pediatric patients. We hypothesized that the change in the renal parenchymal cortex would predict pyeloplasty success. In this study, we aim to measure renal cortical thickness change after pyeloplasty in ureteropelvic junction obstruction patients.Materials and Methods: We retrospectively reviewed 38 patients who underwent pyeloplasty between 2005 and 2019. We divided patients into three age groups and compared the difference of renal parenchymal thickness change by using generalized estimating equations to identify associated factors for renal cortical thickness change after pyeloplasty.Results: Thirty-nine kidney units were identified. The median age at the time of surgery was 41.61± 40.99 months. Generalized estimating equations showed significant change of renal parenchymal thickness over the period of follow-up (p=0.02). The estimate of thickness change was 0.0373 mm/month. Age at the time of surgery was not associated with significant renal cortical thickness over the period of follow-up. The positive predictive factors for renal cortical thickness were creatinine clearance, pre-operative anteroposterior diameter and pre-operative renal differential function. The negative factors for decrease of renal cortical thickness were body weight, presentation with abdominal mass, and history of infection.Conclusion: Renal cortical thickness after pyeloplasty was improved over the period of follow-up. Age at surgery was not associated with improvement of renal parenchymal thickness.Keywords: ureteropelvic junction obstruction, renal parenchymal thickening, ultrasonography, hydronephrosis |
| first_indexed | 2024-12-18T01:11:03Z |
| format | Article |
| id | doaj.art-18bff4644c184fbcb8c1a7bd32d22ae5 |
| institution | Directory Open Access Journal |
| issn | 2253-2447 |
| language | English |
| last_indexed | 2024-12-18T01:11:03Z |
| publishDate | 2021-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Research and Reports in Urology |
| spelling | doaj.art-18bff4644c184fbcb8c1a7bd32d22ae52022-12-21T21:26:06ZengDove Medical PressResearch and Reports in Urology2253-24472021-09-01Volume 1369970468669Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction ObstructionChalieopanyarwong VAttawettayanon WVirote Chalieopanyarwong, Worapat Attawettayanon Division of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, ThailandCorrespondence: Worapat AttawettayanonDivision of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, 90110, ThailandTel +667-445-1428Email aworapat@medicine.psu.ac.thPurpose: The main goal of pyeloplasty is to maintain or improve renal function. Diuretic renography is the gold standard for evaluating renal function after pyeloplasty. Renal ultrasonography (RUS) is commonly used to determine hydronephrosis in pediatric patients. We hypothesized that the change in the renal parenchymal cortex would predict pyeloplasty success. In this study, we aim to measure renal cortical thickness change after pyeloplasty in ureteropelvic junction obstruction patients.Materials and Methods: We retrospectively reviewed 38 patients who underwent pyeloplasty between 2005 and 2019. We divided patients into three age groups and compared the difference of renal parenchymal thickness change by using generalized estimating equations to identify associated factors for renal cortical thickness change after pyeloplasty.Results: Thirty-nine kidney units were identified. The median age at the time of surgery was 41.61± 40.99 months. Generalized estimating equations showed significant change of renal parenchymal thickness over the period of follow-up (p=0.02). The estimate of thickness change was 0.0373 mm/month. Age at the time of surgery was not associated with significant renal cortical thickness over the period of follow-up. The positive predictive factors for renal cortical thickness were creatinine clearance, pre-operative anteroposterior diameter and pre-operative renal differential function. The negative factors for decrease of renal cortical thickness were body weight, presentation with abdominal mass, and history of infection.Conclusion: Renal cortical thickness after pyeloplasty was improved over the period of follow-up. Age at surgery was not associated with improvement of renal parenchymal thickness.Keywords: ureteropelvic junction obstruction, renal parenchymal thickening, ultrasonography, hydronephrosishttps://www.dovepress.com/renal-cortical-thickness-after-pyeloplasty-in-pediatric-ureteropelvic--peer-reviewed-fulltext-article-RRUureteropelvic junction obstructionrenal parenchymal thickeningultrasonographyhydronephrosis |
| spellingShingle | Chalieopanyarwong V Attawettayanon W Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction Research and Reports in Urology ureteropelvic junction obstruction renal parenchymal thickening ultrasonography hydronephrosis |
| title | Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction |
| title_full | Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction |
| title_fullStr | Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction |
| title_full_unstemmed | Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction |
| title_short | Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction |
| title_sort | renal cortical thickness after pyeloplasty in pediatric ureteropelvic junction obstruction |
| topic | ureteropelvic junction obstruction renal parenchymal thickening ultrasonography hydronephrosis |
| url | https://www.dovepress.com/renal-cortical-thickness-after-pyeloplasty-in-pediatric-ureteropelvic--peer-reviewed-fulltext-article-RRU |
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