Constructing benchmark test sets for biological sequence analysis using independent set algorithms.
Biological sequence families contain many sequences that are very similar to each other because they are related by evolution, so the strategy for splitting data into separate training and test sets is a nontrivial choice in benchmarking sequence analysis methods. A random split is insufficient beca...
Main Authors: | Samantha Petti, Sean R Eddy |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-03-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1009492 |
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