When Hypereosinophilia Leads to Stroke
AFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with short-term tissue damage. Thromboembolism is a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2017-04-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | http://ejcrim.com/index.php/EJCRIM/article/view/614 |
| _version_ | 1819142304671203328 |
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| author | Emilie Chalayer Aude Pelissier Bernard Tardy |
| author_facet | Emilie Chalayer Aude Pelissier Bernard Tardy |
| author_sort | Emilie Chalayer |
| collection | DOAJ |
| description | AFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with short-term tissue damage. Thromboembolism is a known cause of death in hypereosinophilic syndrome. A case of Loeffler endocarditis due to FIP1L1-PDGFRA-associated chronic eosinophilic leukemia presenting hemiparesis with fever, which also mislead the initial diagnosis, is reported. |
| first_indexed | 2024-12-22T12:08:13Z |
| format | Article |
| id | doaj.art-18c7c49e4040411fa7ccaa8c86290b1e |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-12-22T12:08:13Z |
| publishDate | 2017-04-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-18c7c49e4040411fa7ccaa8c86290b1e2022-12-21T18:26:22ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942017-04-012010.12890/2017_000614218When Hypereosinophilia Leads to StrokeEmilie Chalayer0Aude Pelissier1Bernard Tardy2Intensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint EtienneIntensive care unit, CHU Saint Etienne, Hopital Nord, 42055 Saint EtienneClinical Investigation Center - CIC 1408, CHU Saint Etienne, FranceAFIP1L1-PDGFRA fusion can only be confirmed through molecular and cytogenetic investigations causing a delay in the diagnosis. However, patients with this mutation need urgent treatment because they present hypereosinophilia which may be associated with short-term tissue damage. Thromboembolism is a known cause of death in hypereosinophilic syndrome. A case of Loeffler endocarditis due to FIP1L1-PDGFRA-associated chronic eosinophilic leukemia presenting hemiparesis with fever, which also mislead the initial diagnosis, is reported.http://ejcrim.com/index.php/EJCRIM/article/view/614Hypereosinophilia, stroke, cytomegalovirus, Loeffer endocarditis |
| spellingShingle | Emilie Chalayer Aude Pelissier Bernard Tardy When Hypereosinophilia Leads to Stroke European Journal of Case Reports in Internal Medicine Hypereosinophilia, stroke, cytomegalovirus, Loeffer endocarditis |
| title | When Hypereosinophilia Leads to Stroke |
| title_full | When Hypereosinophilia Leads to Stroke |
| title_fullStr | When Hypereosinophilia Leads to Stroke |
| title_full_unstemmed | When Hypereosinophilia Leads to Stroke |
| title_short | When Hypereosinophilia Leads to Stroke |
| title_sort | when hypereosinophilia leads to stroke |
| topic | Hypereosinophilia, stroke, cytomegalovirus, Loeffer endocarditis |
| url | http://ejcrim.com/index.php/EJCRIM/article/view/614 |
| work_keys_str_mv | AT emiliechalayer whenhypereosinophilialeadstostroke AT audepelissier whenhypereosinophilialeadstostroke AT bernardtardy whenhypereosinophilialeadstostroke |