Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy
ABSTRACT Introduction: Various preparations can be used in diagnostic cytology, including conventional smears (CS), liquid-based preparations (LBP) and cell block (CB). Objective: The aim of this study is to evaluate the quality of CB preparations in addition to conventional cytological specimens...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Patologia Clínica
2018-02-01
|
| Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442018000100040&tlng=en |
| _version_ | 1798020579960291328 |
|---|---|
| author | Cristina Aparecida T. S. Mitteldorf Rafael S. Vilela Ana Carolina Barros Renata A. Coudry |
| author_facet | Cristina Aparecida T. S. Mitteldorf Rafael S. Vilela Ana Carolina Barros Renata A. Coudry |
| author_sort | Cristina Aparecida T. S. Mitteldorf |
| collection | DOAJ |
| description | ABSTRACT Introduction: Various preparations can be used in diagnostic cytology, including conventional smears (CS), liquid-based preparations (LBP) and cell block (CB). Objective: The aim of this study is to evaluate the quality of CB preparations in addition to conventional cytological specimens in cases of fine-needle aspiration biopsy (FNAB) of thyroid nodules in diagnostic routine. Method: One hundred and six consecutive cases of FNAB routine thyroid nodules were independently evaluated by two cytopathologists (Obs1 and Obs2) on the cellularity of SM, LBP and CB. Results: The cellularity was rich/moderate in 56 (52.8%) CBs for both observers. LBP showed rich/moderate cellularity in 86 (81.1%) cases for Obs1 and 91 (85.8%) for Obs2; among these cases, CB showed the same cellularity in 52/86 (60.4%) cases for Obs1 and 54/91 (59.3%) for Obs2. SM showed rich/moderate cellularity in 86 (81.1%) cases for Obs1 and 87 (82%) for Obs2; among these cases, CB showed the same cellularity in 48/86 (55.8%) cases for Obs1 and 54/87 (62%) for Obs2. CB cellularity was higher than that in LBP in only five cases for Obs1 and three for Obs2. LBP was assessed as low/absent in only five (4.7%) and six (5.6%) cases for Obs1 and Obs2, respectively. Conclusion: CB can be routinely used as additional specimen in material obtained from thyroid nodules FNAB, without adversely affecting LBP specimens, enabling the conduction of further immunohistochemical and molecular studies. |
| first_indexed | 2024-04-11T16:59:51Z |
| format | Article |
| id | doaj.art-18cacfb579b044578f09362d9fe93372 |
| institution | Directory Open Access Journal |
| issn | 1678-4774 |
| language | English |
| last_indexed | 2024-04-11T16:59:51Z |
| publishDate | 2018-02-01 |
| publisher | Sociedade Brasileira de Patologia Clínica |
| record_format | Article |
| series | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| spelling | doaj.art-18cacfb579b044578f09362d9fe933722022-12-22T04:13:10ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1678-47742018-02-01541404510.5935/1676-2444.20180009Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsyCristina Aparecida T. S. MitteldorfRafael S. VilelaAna Carolina BarrosRenata A. CoudryABSTRACT Introduction: Various preparations can be used in diagnostic cytology, including conventional smears (CS), liquid-based preparations (LBP) and cell block (CB). Objective: The aim of this study is to evaluate the quality of CB preparations in addition to conventional cytological specimens in cases of fine-needle aspiration biopsy (FNAB) of thyroid nodules in diagnostic routine. Method: One hundred and six consecutive cases of FNAB routine thyroid nodules were independently evaluated by two cytopathologists (Obs1 and Obs2) on the cellularity of SM, LBP and CB. Results: The cellularity was rich/moderate in 56 (52.8%) CBs for both observers. LBP showed rich/moderate cellularity in 86 (81.1%) cases for Obs1 and 91 (85.8%) for Obs2; among these cases, CB showed the same cellularity in 52/86 (60.4%) cases for Obs1 and 54/91 (59.3%) for Obs2. SM showed rich/moderate cellularity in 86 (81.1%) cases for Obs1 and 87 (82%) for Obs2; among these cases, CB showed the same cellularity in 48/86 (55.8%) cases for Obs1 and 54/87 (62%) for Obs2. CB cellularity was higher than that in LBP in only five cases for Obs1 and three for Obs2. LBP was assessed as low/absent in only five (4.7%) and six (5.6%) cases for Obs1 and Obs2, respectively. Conclusion: CB can be routinely used as additional specimen in material obtained from thyroid nodules FNAB, without adversely affecting LBP specimens, enabling the conduction of further immunohistochemical and molecular studies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442018000100040&tlng=enthyroid glandfine-needle aspiration biopsycytological techniques |
| spellingShingle | Cristina Aparecida T. S. Mitteldorf Rafael S. Vilela Ana Carolina Barros Renata A. Coudry Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy Jornal Brasileiro de Patologia e Medicina Laboratorial thyroid gland fine-needle aspiration biopsy cytological techniques |
| title | Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy |
| title_full | Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy |
| title_fullStr | Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy |
| title_full_unstemmed | Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy |
| title_short | Cell block specimens applied to diagnostic routine of thyroid fine-needle aspiration biopsy |
| title_sort | cell block specimens applied to diagnostic routine of thyroid fine needle aspiration biopsy |
| topic | thyroid gland fine-needle aspiration biopsy cytological techniques |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442018000100040&tlng=en |
| work_keys_str_mv | AT cristinaaparecidatsmitteldorf cellblockspecimensappliedtodiagnosticroutineofthyroidfineneedleaspirationbiopsy AT rafaelsvilela cellblockspecimensappliedtodiagnosticroutineofthyroidfineneedleaspirationbiopsy AT anacarolinabarros cellblockspecimensappliedtodiagnosticroutineofthyroidfineneedleaspirationbiopsy AT renataacoudry cellblockspecimensappliedtodiagnosticroutineofthyroidfineneedleaspirationbiopsy |