Anti-Cancer Properties of Flaxseed Proteome

Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These p...

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Main Authors: Yulia Merkher, Elizaveta Kontareva, Anastasia Alexandrova, Rajesha Javaraiah, Margarita Pustovalova, Sergey Leonov
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/11/4/37
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author Yulia Merkher
Elizaveta Kontareva
Anastasia Alexandrova
Rajesha Javaraiah
Margarita Pustovalova
Sergey Leonov
author_facet Yulia Merkher
Elizaveta Kontareva
Anastasia Alexandrova
Rajesha Javaraiah
Margarita Pustovalova
Sergey Leonov
author_sort Yulia Merkher
collection DOAJ
description Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.
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spelling doaj.art-18cbec5697da4bf1afe41bd3eb37a2942023-12-22T14:37:58ZengMDPI AGProteomes2227-73822023-11-011143710.3390/proteomes11040037Anti-Cancer Properties of Flaxseed ProteomeYulia Merkher0Elizaveta Kontareva1Anastasia Alexandrova2Rajesha Javaraiah3Margarita Pustovalova4Sergey Leonov5School of Biological and Medical Physics, Moscow Institute of Physics and Technology, Dolgoprudny 141700, Moscow Region, RussiaSchool of Biological and Medical Physics, Moscow Institute of Physics and Technology, Dolgoprudny 141700, Moscow Region, RussiaSchool of Biological and Medical Physics, Moscow Institute of Physics and Technology, Dolgoprudny 141700, Moscow Region, RussiaDepartment of Biochemistry, Yuvaraja’s College, University of Mysore Mysuru, Karnataka 570005, IndiaSchool of Biological and Medical Physics, Moscow Institute of Physics and Technology, Dolgoprudny 141700, Moscow Region, RussiaSchool of Biological and Medical Physics, Moscow Institute of Physics and Technology, Dolgoprudny 141700, Moscow Region, RussiaFlaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.https://www.mdpi.com/2227-7382/11/4/37metastasisflaxseed proteinscancer treatmentradiotherapymechanobiologyproteoform level analysis
spellingShingle Yulia Merkher
Elizaveta Kontareva
Anastasia Alexandrova
Rajesha Javaraiah
Margarita Pustovalova
Sergey Leonov
Anti-Cancer Properties of Flaxseed Proteome
Proteomes
metastasis
flaxseed proteins
cancer treatment
radiotherapy
mechanobiology
proteoform level analysis
title Anti-Cancer Properties of Flaxseed Proteome
title_full Anti-Cancer Properties of Flaxseed Proteome
title_fullStr Anti-Cancer Properties of Flaxseed Proteome
title_full_unstemmed Anti-Cancer Properties of Flaxseed Proteome
title_short Anti-Cancer Properties of Flaxseed Proteome
title_sort anti cancer properties of flaxseed proteome
topic metastasis
flaxseed proteins
cancer treatment
radiotherapy
mechanobiology
proteoform level analysis
url https://www.mdpi.com/2227-7382/11/4/37
work_keys_str_mv AT yuliamerkher anticancerpropertiesofflaxseedproteome
AT elizavetakontareva anticancerpropertiesofflaxseedproteome
AT anastasiaalexandrova anticancerpropertiesofflaxseedproteome
AT rajeshajavaraiah anticancerpropertiesofflaxseedproteome
AT margaritapustovalova anticancerpropertiesofflaxseedproteome
AT sergeyleonov anticancerpropertiesofflaxseedproteome