RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions

RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions

Background: Shuanghuanglian injection (SHLI) is a famous Chinese medicine used as an intravenous preparation for the treatment of acute respiratory tract infections. In the recent years, the immediate hypersensitivity reactions induced by SHLI have attracted broad attention. However, the mechanism i...

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Bibliographic Details
Main Authors: Jiayin Han, Yong Zhao, Yushi Zhang, Chunying Li, Yan Yi, Chen Pan, Jingzhuo Tian, Yifei Yang, Hongyu Cui, Lianmei Wang, Suyan Liu, Jing Liu, Nuo Deng, Aihua Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
Shuanghuanglian injection
pseudo-allergic reactions
RhoA/ROCK signaling pathway
vascular leakage
endothelial permeability
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00087/full

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