Amlodipine-induced buccal lichenoid lesions: A case report

Buccal lichenoid lesions (BLLs) are characterised by a unique, linear whitish striation in the buccal region and can be accompanied by ulcers, plaques, erythemas, atrophies and blisters. They are distinguished from oral lichen planus (OLP) by the association of the administration of a drug or contac...

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Main Authors: Muhammad Hafiz Mohamed Pauzi, Azidah Abdul Kadir, Zainab Mat Yudin
Format: Article
Language:English
Published: Academy of Family Physicians of Malaysia 2024-03-01
Series:Malaysian Family Physician
Subjects:
Online Access:https://e-mfp.org/wp-content/uploads/19.17.pdf
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author Muhammad Hafiz Mohamed Pauzi
Azidah Abdul Kadir
Zainab Mat Yudin
author_facet Muhammad Hafiz Mohamed Pauzi
Azidah Abdul Kadir
Zainab Mat Yudin
author_sort Muhammad Hafiz Mohamed Pauzi
collection DOAJ
description Buccal lichenoid lesions (BLLs) are characterised by a unique, linear whitish striation in the buccal region and can be accompanied by ulcers, plaques, erythemas, atrophies and blisters. They are distinguished from oral lichen planus (OLP) by the association of the administration of a drug or contact with a metal. Herein, we present the case of a 42-year-old woman with underlying hypertension with amlodipine-induced BLLs. She complained of a 1-month history of right buccal whitish streaks and oral ulcers 2 months after taking amlodipine. She visited a private otorhinolaryngology clinic, and a biopsy for the right buccal ulcer was conducted. The biopsy result showed features suggestive of OLP. The patient was then diagnosed with OLP. Her symptoms were persistent despite treatment, so a dental referral was made. Amlodipine was suspected as the cause of her condition and was therefore stopped. Her condition gradually resolved after amlodipine withdrawal. Hence, primary care physicians should be aware of BLLs as one of the adverse drug reactions of amlodipine so that prompt management can be taken to avoid further debilitating impacts on patients.
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spelling doaj.art-18cf7c5ed3dd4c0b82df0c683a8ba4112024-04-18T23:07:40ZengAcademy of Family Physicians of MalaysiaMalaysian Family Physician1985-22742024-03-01191710.51866/cr.531Amlodipine-induced buccal lichenoid lesions: A case reportMuhammad Hafiz Mohamed PauziAzidah Abdul KadirZainab Mat YudinBuccal lichenoid lesions (BLLs) are characterised by a unique, linear whitish striation in the buccal region and can be accompanied by ulcers, plaques, erythemas, atrophies and blisters. They are distinguished from oral lichen planus (OLP) by the association of the administration of a drug or contact with a metal. Herein, we present the case of a 42-year-old woman with underlying hypertension with amlodipine-induced BLLs. She complained of a 1-month history of right buccal whitish streaks and oral ulcers 2 months after taking amlodipine. She visited a private otorhinolaryngology clinic, and a biopsy for the right buccal ulcer was conducted. The biopsy result showed features suggestive of OLP. The patient was then diagnosed with OLP. Her symptoms were persistent despite treatment, so a dental referral was made. Amlodipine was suspected as the cause of her condition and was therefore stopped. Her condition gradually resolved after amlodipine withdrawal. Hence, primary care physicians should be aware of BLLs as one of the adverse drug reactions of amlodipine so that prompt management can be taken to avoid further debilitating impacts on patients.https://e-mfp.org/wp-content/uploads/19.17.pdfamlodipineadverse drug reactionlichenoid eruptionslichen planusoral ulcer
spellingShingle Muhammad Hafiz Mohamed Pauzi
Azidah Abdul Kadir
Zainab Mat Yudin
Amlodipine-induced buccal lichenoid lesions: A case report
Malaysian Family Physician
amlodipine
adverse drug reaction
lichenoid eruptions
lichen planus
oral ulcer
title Amlodipine-induced buccal lichenoid lesions: A case report
title_full Amlodipine-induced buccal lichenoid lesions: A case report
title_fullStr Amlodipine-induced buccal lichenoid lesions: A case report
title_full_unstemmed Amlodipine-induced buccal lichenoid lesions: A case report
title_short Amlodipine-induced buccal lichenoid lesions: A case report
title_sort amlodipine induced buccal lichenoid lesions a case report
topic amlodipine
adverse drug reaction
lichenoid eruptions
lichen planus
oral ulcer
url https://e-mfp.org/wp-content/uploads/19.17.pdf
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AT azidahabdulkadir amlodipineinducedbuccallichenoidlesionsacasereport
AT zainabmatyudin amlodipineinducedbuccallichenoidlesionsacasereport