Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma

Bibliographic Details
Main Authors: Pengxing He, Linna Du, Pan Hao, Han Yang, Yufei Ren, Huiqin Kang, Yanli Ding, Wen Zhao, Yichao Xu, Hongmin Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222003026
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author Pengxing He
Linna Du
Pan Hao
Han Yang
Yufei Ren
Huiqin Kang
Yanli Ding
Wen Zhao
Yichao Xu
Hongmin Liu
author_facet Pengxing He
Linna Du
Pan Hao
Han Yang
Yufei Ren
Huiqin Kang
Yanli Ding
Wen Zhao
Yichao Xu
Hongmin Liu
author_sort Pengxing He
collection DOAJ
first_indexed 2024-03-13T00:14:11Z
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institution Directory Open Access Journal
issn 2352-3042
language English
last_indexed 2024-03-13T00:14:11Z
publishDate 2023-09-01
publisher KeAi Communications Co., Ltd.
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spelling doaj.art-18d3a5958e7042e09287af8e6f53ff3e2023-07-12T04:19:40ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422023-09-0110517791782Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinomaPengxing He0Linna Du1Pan Hao2Han Yang3Yufei Ren4Huiqin Kang5Yanli Ding6Wen Zhao7Yichao Xu8Hongmin Liu9Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, ChinaKey Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China; Corresponding author. Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China; Corresponding author. State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China.http://www.sciencedirect.com/science/article/pii/S2352304222003026
spellingShingle Pengxing He
Linna Du
Pan Hao
Han Yang
Yufei Ren
Huiqin Kang
Yanli Ding
Wen Zhao
Yichao Xu
Hongmin Liu
Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
Genes and Diseases
title Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
title_full Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
title_fullStr Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
title_full_unstemmed Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
title_short Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma
title_sort inhibition of lysine specific demethylase 1 lsd1 prevented tumor growth and metastasis by downregulating pd l1 expression in lung adenocarcinoma
url http://www.sciencedirect.com/science/article/pii/S2352304222003026
work_keys_str_mv AT pengxinghe inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT linnadu inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT panhao inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT hanyang inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT yufeiren inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT huiqinkang inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT yanliding inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT wenzhao inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT yichaoxu inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma
AT hongminliu inhibitionoflysinespecificdemethylase1lsd1preventedtumorgrowthandmetastasisbydownregulatingpdl1expressioninlungadenocarcinoma