Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center

Ectopic pancreas is usually a silent gastrointestinal malformation. It may become clinically evident when complicated by chronic inflammation or by growth. More ileal ectopic pancreas has been found in recent years in our hospital. We report the clinical manifestation of ectopic pancreas over the pa...

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Main Authors: Huan-Lin Chen, Wen-Hsiung Chang, Shou-Chuan Shih, Ming-Jong Bair, Shee-Chan Lin
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664609600164
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author Huan-Lin Chen
Wen-Hsiung Chang
Shou-Chuan Shih
Ming-Jong Bair
Shee-Chan Lin
author_facet Huan-Lin Chen
Wen-Hsiung Chang
Shou-Chuan Shih
Ming-Jong Bair
Shee-Chan Lin
author_sort Huan-Lin Chen
collection DOAJ
description Ectopic pancreas is usually a silent gastrointestinal malformation. It may become clinically evident when complicated by chronic inflammation or by growth. More ileal ectopic pancreas has been found in recent years in our hospital. We report the clinical manifestation of ectopic pancreas over the past 22 years. Methods: We reviewed the medical records of patients seen between May 1984 and December 2005 at Mackay Memorial Hospital, with a diagnosis of ectopic pancreas, and extracted clinical and histopathology data from the records. Results: A total of 39 patients (18 male, 21 female; mean age, 46 years) were diagnosed with ectopic pancreas. Most patients were aged between 30 and 50 years. Only 15 (38%) had symptoms suggestive of ectopic pancreas. These included abdominal pain (n = 9), upper gastrointestinal bleeding (n = 5), and abdominal distension (n = 2). The diagnosis in the other 24 patients was made incidentally, usually during surgery for other conditions. While lesions in the stomach were more likely to be diagnosed because of symptoms (12 of 13), lesions in the small bowel were almost always diagnosed incidentally. Only one of eight in the duodenum, one of 10 in the jejunum, and one of eight in the ileum, were isolated findings. One case of ectopic pancreas was detected by capsule endoscopy. Conclusion: Ectopic pancreas can be found in various parts of the gastrointestinal tract. The high proportion of ileal ectopic pancreas is unexpected and needs further study.
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spelling doaj.art-18d409a997c549438af3f04e83e2a8a42022-12-22T01:36:19ZengElsevierJournal of the Formosan Medical Association0929-66462008-12-011071293293610.1016/S0929-6646(09)60016-4Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical CenterHuan-Lin Chen0Wen-Hsiung Chang1Shou-Chuan Shih2Ming-Jong Bair3Shee-Chan Lin4Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taitung Branch, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, TaiwanEctopic pancreas is usually a silent gastrointestinal malformation. It may become clinically evident when complicated by chronic inflammation or by growth. More ileal ectopic pancreas has been found in recent years in our hospital. We report the clinical manifestation of ectopic pancreas over the past 22 years. Methods: We reviewed the medical records of patients seen between May 1984 and December 2005 at Mackay Memorial Hospital, with a diagnosis of ectopic pancreas, and extracted clinical and histopathology data from the records. Results: A total of 39 patients (18 male, 21 female; mean age, 46 years) were diagnosed with ectopic pancreas. Most patients were aged between 30 and 50 years. Only 15 (38%) had symptoms suggestive of ectopic pancreas. These included abdominal pain (n = 9), upper gastrointestinal bleeding (n = 5), and abdominal distension (n = 2). The diagnosis in the other 24 patients was made incidentally, usually during surgery for other conditions. While lesions in the stomach were more likely to be diagnosed because of symptoms (12 of 13), lesions in the small bowel were almost always diagnosed incidentally. Only one of eight in the duodenum, one of 10 in the jejunum, and one of eight in the ileum, were isolated findings. One case of ectopic pancreas was detected by capsule endoscopy. Conclusion: Ectopic pancreas can be found in various parts of the gastrointestinal tract. The high proportion of ileal ectopic pancreas is unexpected and needs further study.http://www.sciencedirect.com/science/article/pii/S0929664609600164capsule endoscopydouble-balloon enteroscopyectopic pancreasgastrointestinal tractsmall intestine
spellingShingle Huan-Lin Chen
Wen-Hsiung Chang
Shou-Chuan Shih
Ming-Jong Bair
Shee-Chan Lin
Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
Journal of the Formosan Medical Association
capsule endoscopy
double-balloon enteroscopy
ectopic pancreas
gastrointestinal tract
small intestine
title Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
title_full Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
title_fullStr Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
title_full_unstemmed Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
title_short Changing Pattern of Ectopic Pancreas: 22 Years of Experience in a Medical Center
title_sort changing pattern of ectopic pancreas 22 years of experience in a medical center
topic capsule endoscopy
double-balloon enteroscopy
ectopic pancreas
gastrointestinal tract
small intestine
url http://www.sciencedirect.com/science/article/pii/S0929664609600164
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AT wenhsiungchang changingpatternofectopicpancreas22yearsofexperienceinamedicalcenter
AT shouchuanshih changingpatternofectopicpancreas22yearsofexperienceinamedicalcenter
AT mingjongbair changingpatternofectopicpancreas22yearsofexperienceinamedicalcenter
AT sheechanlin changingpatternofectopicpancreas22yearsofexperienceinamedicalcenter