PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells

PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells

Mutations in PROP1 are the most common cause of hypopituitarism in humans; therefore, unraveling its mechanism of action is highly relevant from a therapeutic perspective. Our current understanding of the role of PROP1 in the pituitary gland is limited to the repression and activation of the pituita...

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Bibliographic Details
Main Authors: María Inés Pérez Millán, Michelle L Brinkmeier, Amanda H Mortensen, Sally A Camper
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
pituitary
stem cells
hypopituitarism
differentiation
Online Access:https://elifesciences.org/articles/14470

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