A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A<sub>2</sub>
Matrix metalloproteinases (MMPs) are proteolytic enzymes that have been associated with the pathogenesis of inflammatory diseases and obesity. Adipose tissue in turn is an active endocrine organ capable of secreting a range of proinflammatory mediators with autocrine and paracrine properties, which...
Main Authors: | Priscila Motta Janovits, Elbio Leiguez, Viviane Portas, Catarina Teixeira |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/7/921 |
Similar Items
-
A Representative GIIA Phospholipase A<sub>2</sub> Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development
by: Elbio Leiguez, et al.
Published: (2020-11-01) -
Myostatin increases the expression of matrix metalloproteinase genes to promote preadipocytes differentiation in pigs
by: Zhe Zhu, et al.
Published: (2022-12-01) -
The inhibitory effects of Xiao-Gao-Jiang-Zhuo-containing serum on adipogenesis in 3T3-L1 preadipocytes
by: Liang Chen, et al.
Published: (2024-03-01) -
Inflammatory Effects of <i>Bothrops</i> Phospholipases A<sub>2</sub>: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation
by: Vanessa Moreira, et al.
Published: (2021-12-01) -
Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens
by: Karli S, et al.
Published: (2018-10-01)