α-Synuclein Toxicity in <i>Drosophila melanogaster</i> Is Enhanced by the Presence of Iron: Implications for Parkinson’s Disease

α-Synuclein Toxicity in <i>Drosophila melanogaster</i> Is Enhanced by the Presence of Iron: Implications for Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, characterized by the preferential loss of dopaminergic neurons and by the accumulation of intracellular inclusions mainly composed of α-synuclein (α-Syn). While the etiopathogenesis of the disorder is still elusive, recen...

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Bibliographic Details
Main Authors: Francesco Agostini, Luigi Bubacco, Sasanka Chakrabarti, Marco Bisaglia
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Antioxidants
Subjects:
<i>Drosophila melanogaster</i>
ferroptosis
iron
Parkinson’s disease
α-synuclein
Online Access:https://www.mdpi.com/2076-3921/12/2/261

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