Analysis of Intracellular Magnesium and Mineral Depositions during Osteogenic Commitment of 3D Cultured Saos2 Cells

Analysis of Intracellular Magnesium and Mineral Depositions during Osteogenic Commitment of 3D Cultured Saos2 Cells

In this study, we explore the behaviour of intracellular magnesium during bone phenotype modulation in a 3D cell model built to mimic osteogenesis. In addition, we measured the amount of magnesium in the mineral depositions generated during osteogenic induction. A two-fold increase of intracellular...

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Bibliographic Details
Main Authors: Giovanna Picone, Concettina Cappadone, Alice Pasini, Joseph Lovecchio, Marilisa Cortesi, Giovanna Farruggia, Marco Lombardo, Alessandra Gianoncelli, Lucia Mancini, Menk Ralf H., Sandro Donato, Emanuele Giordano, Emil Malucelli, Stefano Iotti
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
osteogenesis
osteoblastic differentiation
osteosarcoma
biomineralization
Online Access:https://www.mdpi.com/1422-0067/21/7/2368

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