Spot diagnosis: An ominous rash in a newborn
<p>Abstract</p> <p>Purpura fulminans (PF) is an ominous cutaneous condition usually associated with meningococcemia. PF in the newborn is rarely reported. We report the case of a female preterm infant with extensive PF due to group B streptococcus (GBS) septicemia. She developed mu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-04-01
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| Series: | Italian Journal of Pediatrics |
| Online Access: | http://www.ijponline.net/content/35/1/10 |
| _version_ | 1818344479680102400 |
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| author | Wong William So King-Woon Hon Kam-Lun Cheung Kam-Lau |
| author_facet | Wong William So King-Woon Hon Kam-Lun Cheung Kam-Lau |
| author_sort | Wong William |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Purpura fulminans (PF) is an ominous cutaneous condition usually associated with meningococcemia. PF in the newborn is rarely reported. We report the case of a female preterm infant with extensive PF due to group B streptococcus (GBS) septicemia. She developed multi-organ system failure despite neonatal intensive care support and succumbed 9 days later. GBS, sensitive to penicillin, was isolated from the blood cultures of the mother and the infant. Invasive early GBS infection is common in the newborn and is empirically treated with prompt institution of intravenous antibiotics. PF associated with GBS is a rare cutaneous sign that must not be missed. Mortality remains high despite aggressive treatment and ICU support.</p> |
| first_indexed | 2024-12-13T16:47:08Z |
| format | Article |
| id | doaj.art-18d9feee24a2447ca78b1db926e6859a |
| institution | Directory Open Access Journal |
| issn | 1720-8424 1824-7288 |
| language | English |
| last_indexed | 2024-12-13T16:47:08Z |
| publishDate | 2009-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj.art-18d9feee24a2447ca78b1db926e6859a2022-12-21T23:38:07ZengBMCItalian Journal of Pediatrics1720-84241824-72882009-04-013511010.1186/1824-7288-35-10Spot diagnosis: An ominous rash in a newbornWong WilliamSo King-WoonHon Kam-LunCheung Kam-Lau<p>Abstract</p> <p>Purpura fulminans (PF) is an ominous cutaneous condition usually associated with meningococcemia. PF in the newborn is rarely reported. We report the case of a female preterm infant with extensive PF due to group B streptococcus (GBS) septicemia. She developed multi-organ system failure despite neonatal intensive care support and succumbed 9 days later. GBS, sensitive to penicillin, was isolated from the blood cultures of the mother and the infant. Invasive early GBS infection is common in the newborn and is empirically treated with prompt institution of intravenous antibiotics. PF associated with GBS is a rare cutaneous sign that must not be missed. Mortality remains high despite aggressive treatment and ICU support.</p>http://www.ijponline.net/content/35/1/10 |
| spellingShingle | Wong William So King-Woon Hon Kam-Lun Cheung Kam-Lau Spot diagnosis: An ominous rash in a newborn Italian Journal of Pediatrics |
| title | Spot diagnosis: An ominous rash in a newborn |
| title_full | Spot diagnosis: An ominous rash in a newborn |
| title_fullStr | Spot diagnosis: An ominous rash in a newborn |
| title_full_unstemmed | Spot diagnosis: An ominous rash in a newborn |
| title_short | Spot diagnosis: An ominous rash in a newborn |
| title_sort | spot diagnosis an ominous rash in a newborn |
| url | http://www.ijponline.net/content/35/1/10 |
| work_keys_str_mv | AT wongwilliam spotdiagnosisanominousrashinanewborn AT sokingwoon spotdiagnosisanominousrashinanewborn AT honkamlun spotdiagnosisanominousrashinanewborn AT cheungkamlau spotdiagnosisanominousrashinanewborn |