Shikimic acid protects against doxorubicin-induced cardiotoxicity in rats

Shikimic acid protects against doxorubicin-induced cardiotoxicity in rats

Abstract Doxorubicin (DOX) is used to treat a variety of malignancies; however, its cardiotoxicity limits its effectiveness. Shikimic acid (SA) showed several promising biomedical applications. This study investigated the protective effect of SA on DOX-induced cardiotoxicity in male rats. The ADMETl...

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Bibliographic Details
Main Authors: Maha Abdullah Alwaili, Amal S. Abu-Almakarem, Karim Samy El-Said, Thamir M. Eid, Maysa A. Mobasher, Ashwaq Hassan Alsabban, Najla Ali Alburae, Abeer A. Banjabi, Mohamed Mostafa Soliman
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Shikimic acid
Antioxidants
Doxorubicin
Docking cardiotoxicity
Online Access:https://doi.org/10.1038/s41598-025-90549-4

Internet

https://doi.org/10.1038/s41598-025-90549-4

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