Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study

Corona virus disease-19 (COVID-19) vaccines have been approved for emergency use. Ocular adverse effects following the vaccines have been reported. Purpose: To report an unique case of recurrent central serous chorioretinopathy following both doses of COVID-19 vaccine. Observations: A 40-year-old ma...

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Main Authors: Srinivasan Sanjay, Isha Acharya, Ankush Kawali, Rohit Shetty, Padmamalini Mahendradas
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993622003905
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author Srinivasan Sanjay
Isha Acharya
Ankush Kawali
Rohit Shetty
Padmamalini Mahendradas
author_facet Srinivasan Sanjay
Isha Acharya
Ankush Kawali
Rohit Shetty
Padmamalini Mahendradas
author_sort Srinivasan Sanjay
collection DOAJ
description Corona virus disease-19 (COVID-19) vaccines have been approved for emergency use. Ocular adverse effects following the vaccines have been reported. Purpose: To report an unique case of recurrent central serous chorioretinopathy following both doses of COVID-19 vaccine. Observations: A 40-year-old male presented with blurring of vision in the left eye during 2 days following COVISHIELD™ (Serum Institute of India). He had a previous history of central serous chorioretinopathy in the right eye 2 years back and was treated with micropulse laser. Ocular examination showed a best corrected visual acuity of 20/20 right eye and 20/60 left eye. Fundus evaluation of left eye showed central serous chorioretinopathy. Spectral domain optical coherence tomography of the left eye revealed neurosensory detachment. Fundus fluorescein angiography of the left eye showed multiple window defects and ink-blot appearance in the macula. Oral eplerenone 50mg once a day for a month showed significant reduction in the subretinal fluid. Patient developed central serous chorioretinopathy in the left eye 3 days after 2nd dose of COVISHIELD™. Conclusion and Importance: CSCR following vaccination may be a temporal event. In our patient it occurred following the vaccination. This is the first case of a recurrent CSCR after either dose of COVID-19 vaccination. Ocular symptoms after vaccination warrant a thorough eye evaluation.
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spelling doaj.art-18dbd00c60014c98ac562e3d9a946b4b2022-12-22T02:16:18ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-09-0127101644Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging studySrinivasan Sanjay0Isha Acharya1Ankush Kawali2Rohit Shetty3Padmamalini Mahendradas4Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, India; Corresponding author. 121/C, Chord Road, Narayana Nethralaya, Bangalore, India.Department of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, IndiaDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, IndiaDepartments of Cornea, Refractive Surgery and Neuro-Ophthalmology Narayana Nethralaya, Bangalore, IndiaDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, IndiaCorona virus disease-19 (COVID-19) vaccines have been approved for emergency use. Ocular adverse effects following the vaccines have been reported. Purpose: To report an unique case of recurrent central serous chorioretinopathy following both doses of COVID-19 vaccine. Observations: A 40-year-old male presented with blurring of vision in the left eye during 2 days following COVISHIELD™ (Serum Institute of India). He had a previous history of central serous chorioretinopathy in the right eye 2 years back and was treated with micropulse laser. Ocular examination showed a best corrected visual acuity of 20/20 right eye and 20/60 left eye. Fundus evaluation of left eye showed central serous chorioretinopathy. Spectral domain optical coherence tomography of the left eye revealed neurosensory detachment. Fundus fluorescein angiography of the left eye showed multiple window defects and ink-blot appearance in the macula. Oral eplerenone 50mg once a day for a month showed significant reduction in the subretinal fluid. Patient developed central serous chorioretinopathy in the left eye 3 days after 2nd dose of COVISHIELD™. Conclusion and Importance: CSCR following vaccination may be a temporal event. In our patient it occurred following the vaccination. This is the first case of a recurrent CSCR after either dose of COVID-19 vaccination. Ocular symptoms after vaccination warrant a thorough eye evaluation.http://www.sciencedirect.com/science/article/pii/S2451993622003905COVID-19 vaccinationCOVISHIELD™Central serous chorioretinopathySpectral domain optical coherence tomographyEplerenone
spellingShingle Srinivasan Sanjay
Isha Acharya
Ankush Kawali
Rohit Shetty
Padmamalini Mahendradas
Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
American Journal of Ophthalmology Case Reports
COVID-19 vaccination
COVISHIELD™
Central serous chorioretinopathy
Spectral domain optical coherence tomography
Eplerenone
title Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
title_full Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
title_fullStr Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
title_full_unstemmed Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
title_short Unilateral recurrent central serous chorioretinopathy (CSCR) following COVID-19 vaccination- A multimodal imaging study
title_sort unilateral recurrent central serous chorioretinopathy cscr following covid 19 vaccination a multimodal imaging study
topic COVID-19 vaccination
COVISHIELD™
Central serous chorioretinopathy
Spectral domain optical coherence tomography
Eplerenone
url http://www.sciencedirect.com/science/article/pii/S2451993622003905
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