RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA
Abstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/617 |
| _version_ | 1826534242623946752 |
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| author | E. N. Suprun V. K. Kozlov |
| author_facet | E. N. Suprun V. K. Kozlov |
| author_sort | E. N. Suprun |
| collection | DOAJ |
| description | Abstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage according on CMV antibodies titers. The study has revealed that such regimen of antibody administration based on the content of anti-CMV antibodies in bronchial asthma treatment stops active CMV replication in bronchial mucous membrane, alleviates clinical course of the disease, diminishes changes of immune system typical to children suffering from bronchial asthma and CMV reactivation, thus allowing to reduce the volume of basic therapy, along with maintaining control of asthma control. |
| first_indexed | 2024-03-08T05:50:23Z |
| format | Article |
| id | doaj.art-18dd9d779875460cbcfde2357cf63e55 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2025-03-14T02:19:55Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-18dd9d779875460cbcfde2357cf63e552025-03-11T17:59:05ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0115326927610.15789/1563-0625-2013-3-269-276614RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMAE. N. Suprun0V. K. Kozlov1Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, KhabarovskFar Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, KhabarovskAbstract. We propose a protocol of treatment in cases of bronchial asthma with cytomegalovirus (CMV) persistence. This basic therapy is administered depending on the disease severity, according to the National Programme 2009. The treatment includes administration of human immunoglobulin, with dosage according on CMV antibodies titers. The study has revealed that such regimen of antibody administration based on the content of anti-CMV antibodies in bronchial asthma treatment stops active CMV replication in bronchial mucous membrane, alleviates clinical course of the disease, diminishes changes of immune system typical to children suffering from bronchial asthma and CMV reactivation, thus allowing to reduce the volume of basic therapy, along with maintaining control of asthma control.https://www.mimmun.ru/mimmun/article/view/617bronchial asthmacytomegalovirusimmunitychildren |
| spellingShingle | E. N. Suprun V. K. Kozlov RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA Медицинская иммунология bronchial asthma cytomegalovirus immunity children |
| title | RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA |
| title_full | RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA |
| title_fullStr | RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA |
| title_full_unstemmed | RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA |
| title_short | RATIONALE FOR A SPECIFIC THERAPY OF CYTOMEGALOVIRUS INFECTION IN CHILDREN WITH BRONCHIAL ASTHMA |
| title_sort | rationale for a specific therapy of cytomegalovirus infection in children with bronchial asthma |
| topic | bronchial asthma cytomegalovirus immunity children |
| url | https://www.mimmun.ru/mimmun/article/view/617 |
| work_keys_str_mv | AT ensuprun rationaleforaspecifictherapyofcytomegalovirusinfectioninchildrenwithbronchialasthma AT vkkozlov rationaleforaspecifictherapyofcytomegalovirusinfectioninchildrenwithbronchialasthma |