320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection.
OBJECTIVE:To reduce the iodine load required for CT Transcatheter Aortic Valve Replacement (TAVR) planning on a 320-row scanner by acquiring the two CT TAVR steps (ECG-gated aortic root CTA and non-gated aorto-ilio-femoral CTA) within a single contrast media bolus injection. METHODS:50 consecutive p...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC6136810?pdf=render |
| _version_ | 1818209637967593472 |
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| author | Daddy Mata-Mbemba Aissam Labani Soraya El Ghannudi Mi-Young Jeung Patrick Ohlmann Catherine Roy Mickaël Ohana |
| author_facet | Daddy Mata-Mbemba Aissam Labani Soraya El Ghannudi Mi-Young Jeung Patrick Ohlmann Catherine Roy Mickaël Ohana |
| author_sort | Daddy Mata-Mbemba |
| collection | DOAJ |
| description | OBJECTIVE:To reduce the iodine load required for CT Transcatheter Aortic Valve Replacement (TAVR) planning on a 320-row scanner by acquiring the two CT TAVR steps (ECG-gated aortic root CTA and non-gated aorto-ilio-femoral CTA) within a single contrast media bolus injection. METHODS:50 consecutive patients (82.6±6.9 years; 56% female) were prospectively enrolled and underwent a TAVR planning using a 320-row CT, with ECG-gated aortic root CTA immediately followed by a non-gated aorto-iliac acquisition, all within a single bolus of 40-70mL of Iohexol 350mgI/mL. The Iodine load, image quality, SNR, CNR and radiation dose were compared using a Mann-Whitney test to that of 24 consecutive patients (84.3±4.8 years, 58% female) previously imaged on a 64-row scanner with a conventional two-step protocol. RESULTS:Iodine load was reduced by 44%. All examinations were of diagnostic quality, with improvement of the aortic root CTA image quality (4.9±0.3 versus 4.6±0.5, p<0.01) and a non-significant decrease of the aorto-iliac CTA image quality (4.7±0.6 versus 4.9±0.3, p = 0.07). SNR and CNR were significantly improved in the aortic root CTA (14.0±5.3 and 10.4±4.5 versus 10.3±4.2 and 6.8±3.3, p<0.01 for both) and non-significantly higher in the aorto-iliac CTA (16.5±8.0 and 14.1±7.9 versus 14.7±5.5 and 12.5±5.0, p = 0.42 and p = 0.66). Total radiation dose was reduced by 32%. CONCLUSION:320-row CT scanner enables a 44% reduction of iodine load in TAVR planning, while maintaining excellent aorto-ilio-femoral arterial enhancement and lowering radiation dose. |
| first_indexed | 2024-12-12T05:03:53Z |
| format | Article |
| id | doaj.art-18dda13a2ca54bf6871b4b86cefb2565 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T05:03:53Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-18dda13a2ca54bf6871b4b86cefb25652022-12-22T00:37:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01139e020414510.1371/journal.pone.0204145320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection.Daddy Mata-MbembaAissam LabaniSoraya El GhannudiMi-Young JeungPatrick OhlmannCatherine RoyMickaël OhanaOBJECTIVE:To reduce the iodine load required for CT Transcatheter Aortic Valve Replacement (TAVR) planning on a 320-row scanner by acquiring the two CT TAVR steps (ECG-gated aortic root CTA and non-gated aorto-ilio-femoral CTA) within a single contrast media bolus injection. METHODS:50 consecutive patients (82.6±6.9 years; 56% female) were prospectively enrolled and underwent a TAVR planning using a 320-row CT, with ECG-gated aortic root CTA immediately followed by a non-gated aorto-iliac acquisition, all within a single bolus of 40-70mL of Iohexol 350mgI/mL. The Iodine load, image quality, SNR, CNR and radiation dose were compared using a Mann-Whitney test to that of 24 consecutive patients (84.3±4.8 years, 58% female) previously imaged on a 64-row scanner with a conventional two-step protocol. RESULTS:Iodine load was reduced by 44%. All examinations were of diagnostic quality, with improvement of the aortic root CTA image quality (4.9±0.3 versus 4.6±0.5, p<0.01) and a non-significant decrease of the aorto-iliac CTA image quality (4.7±0.6 versus 4.9±0.3, p = 0.07). SNR and CNR were significantly improved in the aortic root CTA (14.0±5.3 and 10.4±4.5 versus 10.3±4.2 and 6.8±3.3, p<0.01 for both) and non-significantly higher in the aorto-iliac CTA (16.5±8.0 and 14.1±7.9 versus 14.7±5.5 and 12.5±5.0, p = 0.42 and p = 0.66). Total radiation dose was reduced by 32%. CONCLUSION:320-row CT scanner enables a 44% reduction of iodine load in TAVR planning, while maintaining excellent aorto-ilio-femoral arterial enhancement and lowering radiation dose.http://europepmc.org/articles/PMC6136810?pdf=render |
| spellingShingle | Daddy Mata-Mbemba Aissam Labani Soraya El Ghannudi Mi-Young Jeung Patrick Ohlmann Catherine Roy Mickaël Ohana 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. PLoS ONE |
| title | 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. |
| title_full | 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. |
| title_fullStr | 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. |
| title_full_unstemmed | 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. |
| title_short | 320-row CT transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection. |
| title_sort | 320 row ct transcatheter aortic valve replacement planning with a single reduced contrast media bolus injection |
| url | http://europepmc.org/articles/PMC6136810?pdf=render |
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