Composition of human cerebrospinal fluid cerebroside
A technique was developed to isolate sufficient material for compositional analysis of cerebroside from pooled human cerebrospinal fluid. The carbohydrate moiety was principally galactose. The sphingosine base and fatty acid compositions were found to be similar to that of brain cerebroside. The pre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1971-03-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520395237 |
| _version_ | 1830187238389972992 |
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| author | YOSHITAKA NAGAI JULIAN N. KANFERS |
| author_facet | YOSHITAKA NAGAI JULIAN N. KANFERS |
| author_sort | YOSHITAKA NAGAI |
| collection | DOAJ |
| description | A technique was developed to isolate sufficient material for compositional analysis of cerebroside from pooled human cerebrospinal fluid. The carbohydrate moiety was principally galactose. The sphingosine base and fatty acid compositions were found to be similar to that of brain cerebroside. The presence of a contaminant in commercial silica gel which chromatographed like the trimethylsilyl derivative of glucose is described. |
| first_indexed | 2024-12-17T22:25:05Z |
| format | Article |
| id | doaj.art-18de6e20dea44b99a0598d0ed4a759f0 |
| institution | Directory Open Access Journal |
| issn | 0022-2275 |
| language | English |
| last_indexed | 2024-12-17T22:25:05Z |
| publishDate | 1971-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Lipid Research |
| spelling | doaj.art-18de6e20dea44b99a0598d0ed4a759f02022-12-21T21:30:22ZengElsevierJournal of Lipid Research0022-22751971-03-01122143148Composition of human cerebrospinal fluid cerebrosideYOSHITAKA NAGAI0JULIAN N. KANFERS1Neurology Research and Joseph P. Kennedy, Jr. Memorial Laboratories, Massachusetts General Hospital, Boston, Massachusetts 02114Neurology Research and Joseph P. Kennedy, Jr. Memorial Laboratories, Massachusetts General Hospital, Boston, Massachusetts 02114A technique was developed to isolate sufficient material for compositional analysis of cerebroside from pooled human cerebrospinal fluid. The carbohydrate moiety was principally galactose. The sphingosine base and fatty acid compositions were found to be similar to that of brain cerebroside. The presence of a contaminant in commercial silica gel which chromatographed like the trimethylsilyl derivative of glucose is described.http://www.sciencedirect.com/science/article/pii/S0022227520395237sphingolipid isolation |
| spellingShingle | YOSHITAKA NAGAI JULIAN N. KANFERS Composition of human cerebrospinal fluid cerebroside Journal of Lipid Research sphingolipid isolation |
| title | Composition of human cerebrospinal fluid cerebroside |
| title_full | Composition of human cerebrospinal fluid cerebroside |
| title_fullStr | Composition of human cerebrospinal fluid cerebroside |
| title_full_unstemmed | Composition of human cerebrospinal fluid cerebroside |
| title_short | Composition of human cerebrospinal fluid cerebroside |
| title_sort | composition of human cerebrospinal fluid cerebroside |
| topic | sphingolipid isolation |
| url | http://www.sciencedirect.com/science/article/pii/S0022227520395237 |
| work_keys_str_mv | AT yoshitakanagai compositionofhumancerebrospinalfluidcerebroside AT juliannkanfers compositionofhumancerebrospinalfluidcerebroside |