The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases
In the treatment of intracanal and periodontal infections, the local application of antibiotics and other therapeutic agents in the root canal or in periodontal pockets may be a promising approach to achieve sustained drug release, high antimicrobial activity and low systemic side effects. Micropart...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-08-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1999-4923/3/3/538/ |
| _version_ | 1811300044453707776 |
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| author | José Blanco Méndez Asteria Luzardo Álvarez Francisco Otero Espinar |
| author_facet | José Blanco Méndez Asteria Luzardo Álvarez Francisco Otero Espinar |
| author_sort | José Blanco Méndez |
| collection | DOAJ |
| description | In the treatment of intracanal and periodontal infections, the local application of antibiotics and other therapeutic agents in the root canal or in periodontal pockets may be a promising approach to achieve sustained drug release, high antimicrobial activity and low systemic side effects. Microparticles made from biodegradable polymers have been reported to be an effective means of delivering antibacterial drugs in endodontic and periodontal therapy. The aim of this review article is to assess recent therapeutic strategies in which biocompatible microparticles are used for effective management of periodontal and endodontic diseases. In vitro and in vivo studies that have investigated the biocompatibility or efficacy of certain microparticle formulations and devices are presented. Future directions in the application of microencapsulation techniques in endodontic and periodontal therapies are discussed. |
| first_indexed | 2024-04-13T06:45:26Z |
| format | Article |
| id | doaj.art-18df7336fca64592b6fef447e830f169 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-04-13T06:45:26Z |
| publishDate | 2011-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-18df7336fca64592b6fef447e830f1692022-12-22T02:57:36ZengMDPI AGPharmaceutics1999-49232011-08-013353857110.3390/pharmaceutics3030538The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal DiseasesJosé Blanco MéndezAsteria Luzardo ÁlvarezFrancisco Otero EspinarIn the treatment of intracanal and periodontal infections, the local application of antibiotics and other therapeutic agents in the root canal or in periodontal pockets may be a promising approach to achieve sustained drug release, high antimicrobial activity and low systemic side effects. Microparticles made from biodegradable polymers have been reported to be an effective means of delivering antibacterial drugs in endodontic and periodontal therapy. The aim of this review article is to assess recent therapeutic strategies in which biocompatible microparticles are used for effective management of periodontal and endodontic diseases. In vitro and in vivo studies that have investigated the biocompatibility or efficacy of certain microparticle formulations and devices are presented. Future directions in the application of microencapsulation techniques in endodontic and periodontal therapies are discussed.http://www.mdpi.com/1999-4923/3/3/538/microencapsulationperiodontal diseasesendodontic failureperiodontal pocketroot canalcontrolled release |
| spellingShingle | José Blanco Méndez Asteria Luzardo Álvarez Francisco Otero Espinar The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases Pharmaceutics microencapsulation periodontal diseases endodontic failure periodontal pocket root canal controlled release |
| title | The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases |
| title_full | The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases |
| title_fullStr | The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases |
| title_full_unstemmed | The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases |
| title_short | The Application of Microencapsulation Techniques in the Treatment of Endodontic and Periodontal Diseases |
| title_sort | application of microencapsulation techniques in the treatment of endodontic and periodontal diseases |
| topic | microencapsulation periodontal diseases endodontic failure periodontal pocket root canal controlled release |
| url | http://www.mdpi.com/1999-4923/3/3/538/ |
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