Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients
The study was conducted with the participation of 47 healthy subjects and 48 schizophrenia patients. The different effects of Val158Met polymorphism have been found in the control and patients groups. The increased N100 amplitude and minimal number of the error responses in oddball task were reveale...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2019-12-01
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| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| Subjects: | |
| Online Access: | https://www.bekhterevreview.com/jour/article/view/326 |
| _version_ | 1797698808935612416 |
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| author | A. A. Fedotova A. V. Kirenskaya |
| author_facet | A. A. Fedotova A. V. Kirenskaya |
| author_sort | A. A. Fedotova |
| collection | DOAJ |
| description | The study was conducted with the participation of 47 healthy subjects and 48 schizophrenia patients. The different effects of Val158Met polymorphism have been found in the control and patients groups. The increased N100 amplitude and minimal number of the error responses in oddball task were revealed in healthy subjects with Val/Val genotype. In patients group Val/Val genotype was related to the decreased N100 amplitude and worse performance of oddball task. |
| first_indexed | 2024-03-12T03:59:23Z |
| format | Article |
| id | doaj.art-18dfd741a3d94c058e957f1b0da3c28f |
| institution | Directory Open Access Journal |
| issn | 2313-7053 2713-055X |
| language | Russian |
| last_indexed | 2024-03-12T03:59:23Z |
| publishDate | 2019-12-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj.art-18dfd741a3d94c058e957f1b0da3c28f2023-09-03T11:45:19ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2019-12-0104-110911110.31363/2313-7053-2019-4-1-109-111305Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patientsA. A. Fedotova0A. V. Kirenskaya1Lomonosov Moscow State UniversityFederal State Budgetary Institution “V. Serbsky National Medical Research Centre for Psychiatry and Narcology” of the Ministry of Health of the Russian FederationThe study was conducted with the participation of 47 healthy subjects and 48 schizophrenia patients. The different effects of Val158Met polymorphism have been found in the control and patients groups. The increased N100 amplitude and minimal number of the error responses in oddball task were revealed in healthy subjects with Val/Val genotype. In patients group Val/Val genotype was related to the decreased N100 amplitude and worse performance of oddball task.https://www.bekhterevreview.com/jour/article/view/326val158met polymorphism of the comt gene, auditory evoked potential n100, schizophrenia |
| spellingShingle | A. A. Fedotova A. V. Kirenskaya Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева val158met polymorphism of the comt gene, auditory evoked potential n100, schizophrenia |
| title | Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| title_full | Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| title_fullStr | Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| title_full_unstemmed | Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| title_short | Effects of the COMT Val158Met polymorphism on N100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| title_sort | effects of the comt val158met polymorphism on n100 component of auditory evoked potential and oddball task performance in healthy subjects and schizophrenia patients |
| topic | val158met polymorphism of the comt gene, auditory evoked potential n100, schizophrenia |
| url | https://www.bekhterevreview.com/jour/article/view/326 |
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