Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis

Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness...

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Bibliographic Details
Main Authors: Vikas Gupta, Anjani Kumar Sharma, Rajendra Kumar Sureka, Sushant Kumar Bhuyan, Prashant Kumar Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Annals of Indian Academy of Neurology
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Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=Gupta
Description
Summary:Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener′s granulomatosis should be considered in the differential diagnosis of chronic meningitis.
ISSN:0972-2327
1998-3549