Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2013-01-01
|
Series: | Annals of Indian Academy of Neurology |
Subjects: | |
Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=Gupta |
_version_ | 1818526156523044864 |
---|---|
author | Vikas Gupta Anjani Kumar Sharma Rajendra Kumar Sureka Sushant Kumar Bhuyan Prashant Kumar Singh |
author_facet | Vikas Gupta Anjani Kumar Sharma Rajendra Kumar Sureka Sushant Kumar Bhuyan Prashant Kumar Singh |
author_sort | Vikas Gupta |
collection | DOAJ |
description | Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener′s granulomatosis should be considered in the differential diagnosis of chronic meningitis. |
first_indexed | 2024-12-11T06:19:00Z |
format | Article |
id | doaj.art-18e1b05b2546479184196f2551e10076 |
institution | Directory Open Access Journal |
issn | 0972-2327 1998-3549 |
language | English |
last_indexed | 2024-12-11T06:19:00Z |
publishDate | 2013-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Annals of Indian Academy of Neurology |
spelling | doaj.art-18e1b05b2546479184196f2551e100762022-12-22T01:17:53ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492013-01-0116341141310.4103/0972-2327.116920Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosisVikas GuptaAnjani Kumar SharmaRajendra Kumar SurekaSushant Kumar BhuyanPrashant Kumar SinghWegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener′s granulomatosis should be considered in the differential diagnosis of chronic meningitis.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=GuptaChronic meningitiscranial neuropathiesWegener′s granulomatosis |
spellingShingle | Vikas Gupta Anjani Kumar Sharma Rajendra Kumar Sureka Sushant Kumar Bhuyan Prashant Kumar Singh Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis Annals of Indian Academy of Neurology Chronic meningitis cranial neuropathies Wegener′s granulomatosis |
title | Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis |
title_full | Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis |
title_fullStr | Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis |
title_full_unstemmed | Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis |
title_short | Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis |
title_sort | chronic meningitis with multiple cranial neuropathies a rare initial presentation of wegener s granulomatosis |
topic | Chronic meningitis cranial neuropathies Wegener′s granulomatosis |
url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=Gupta |
work_keys_str_mv | AT vikasgupta chronicmeningitiswithmultiplecranialneuropathiesarareinitialpresentationofwegenersgranulomatosis AT anjanikumarsharma chronicmeningitiswithmultiplecranialneuropathiesarareinitialpresentationofwegenersgranulomatosis AT rajendrakumarsureka chronicmeningitiswithmultiplecranialneuropathiesarareinitialpresentationofwegenersgranulomatosis AT sushantkumarbhuyan chronicmeningitiswithmultiplecranialneuropathiesarareinitialpresentationofwegenersgranulomatosis AT prashantkumarsingh chronicmeningitiswithmultiplecranialneuropathiesarareinitialpresentationofwegenersgranulomatosis |