Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis

Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness...

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Main Authors: Vikas Gupta, Anjani Kumar Sharma, Rajendra Kumar Sureka, Sushant Kumar Bhuyan, Prashant Kumar Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=Gupta
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author Vikas Gupta
Anjani Kumar Sharma
Rajendra Kumar Sureka
Sushant Kumar Bhuyan
Prashant Kumar Singh
author_facet Vikas Gupta
Anjani Kumar Sharma
Rajendra Kumar Sureka
Sushant Kumar Bhuyan
Prashant Kumar Singh
author_sort Vikas Gupta
collection DOAJ
description Wegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener′s granulomatosis should be considered in the differential diagnosis of chronic meningitis.
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1998-3549
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spelling doaj.art-18e1b05b2546479184196f2551e100762022-12-22T01:17:53ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492013-01-0116341141310.4103/0972-2327.116920Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosisVikas GuptaAnjani Kumar SharmaRajendra Kumar SurekaSushant Kumar BhuyanPrashant Kumar SinghWegener′s granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener′s granulomatosis should be considered in the differential diagnosis of chronic meningitis.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=GuptaChronic meningitiscranial neuropathiesWegener′s granulomatosis
spellingShingle Vikas Gupta
Anjani Kumar Sharma
Rajendra Kumar Sureka
Sushant Kumar Bhuyan
Prashant Kumar Singh
Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
Annals of Indian Academy of Neurology
Chronic meningitis
cranial neuropathies
Wegener′s granulomatosis
title Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
title_full Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
title_fullStr Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
title_full_unstemmed Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
title_short Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener′s granulomatosis
title_sort chronic meningitis with multiple cranial neuropathies a rare initial presentation of wegener s granulomatosis
topic Chronic meningitis
cranial neuropathies
Wegener′s granulomatosis
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=3;spage=411;epage=413;aulast=Gupta
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