What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review.
ABSTRACT: Objectives: In recent years, outbreaks and a rising incidence of diphtheria, tetanus, and pertussis have occurred in Asia, particularly in older children. Methods: A systematic search of MEDLINE and Embase was conducted from January 2000 to October 2020 to identify the epidemiology of dip...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971222000534 |
| _version_ | 1818776324975624192 |
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| author | Lindsay Nicholson Elizabeth Adkins Mulya Rahma Karyanti Anna Ong-Lim Bhaskar Shenoy Catherine Huoi Juan C. Vargas-Zambrano |
| author_facet | Lindsay Nicholson Elizabeth Adkins Mulya Rahma Karyanti Anna Ong-Lim Bhaskar Shenoy Catherine Huoi Juan C. Vargas-Zambrano |
| author_sort | Lindsay Nicholson |
| collection | DOAJ |
| description | ABSTRACT: Objectives: In recent years, outbreaks and a rising incidence of diphtheria, tetanus, and pertussis have occurred in Asia, particularly in older children. Methods: A systematic search of MEDLINE and Embase was conducted from January 2000 to October 2020 to identify the epidemiology of diphtheria, tetanus, pertussis, and poliomyelitis in children and adolescents (aged 3–18 years) in Asia. The results were then related to vaccination schedules, booster coverage rates, pertussis source of infection, and booster immunogenicity, as identified by a pragmatic review. The International Prospective Register of Systematic Reviews (PROSPERO) registration: #CRD42020222445. Results: A total of 35 studies were included in this review. Limited data were reported on the epidemiology of diphtheria, tetanus, pertussis, and poliomyelitis. Data from studies reporting the incidence of diphtheria and pertussis exemplify the shift in epidemiology to older children/adolescents. Seroprevalence data suggest that immunity to pertussis and diphtheria is below the level of herd immunity in several Asian countries in this population. Conclusion: The true burden of diphtheria, pertussis, and tetanus in children aged 3-18 years in Asia is unknown because of weak or absent nationwide surveillance systems. The available evidence highlights the inadequacies in immunity, either by gaps in a recommendation or suboptimal booster coverage, supporting the public health need for booster vaccinations in this population. |
| first_indexed | 2024-12-18T11:11:08Z |
| format | Article |
| id | doaj.art-18e2917b546b4c659e1496ea2a3854e6 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-18T11:11:08Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-18e2917b546b4c659e1496ea2a3854e62022-12-21T21:09:59ZengElsevierInternational Journal of Infectious Diseases1201-97122022-04-01117116129What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review.Lindsay Nicholson0Elizabeth Adkins1Mulya Rahma Karyanti2Anna Ong-Lim3Bhaskar Shenoy4Catherine Huoi5Juan C. Vargas-Zambrano6Maverex Limited, Newcastle upon Tyne, United KingdomMaverex Limited, Newcastle upon Tyne, United KingdomDepartment of Child Health, Medical Faculty University of Indonesia, Jakarta, Indonesia.Infectious and Tropical Disease Division, Department of Pediatrics, College of Medicine - Philippine General Hospital, University of the Philippines, ManilaDepartment of Pediatrics & Chief, Division of Pediatric Infectious Diseases Manipal Hospital, Bangalore, IndiaSanofi Pasteur, 14 espace Henry Vallée, 69007 Lyon, FranceSanofi Pasteur, 14 espace Henry Vallée, 69007 Lyon, France; Corresponding author. Juan C. Vargas-Zambrano MD. Sanofi Pasteur, 14 Espace Henri Valle, Lyon, 69002, FranceABSTRACT: Objectives: In recent years, outbreaks and a rising incidence of diphtheria, tetanus, and pertussis have occurred in Asia, particularly in older children. Methods: A systematic search of MEDLINE and Embase was conducted from January 2000 to October 2020 to identify the epidemiology of diphtheria, tetanus, pertussis, and poliomyelitis in children and adolescents (aged 3–18 years) in Asia. The results were then related to vaccination schedules, booster coverage rates, pertussis source of infection, and booster immunogenicity, as identified by a pragmatic review. The International Prospective Register of Systematic Reviews (PROSPERO) registration: #CRD42020222445. Results: A total of 35 studies were included in this review. Limited data were reported on the epidemiology of diphtheria, tetanus, pertussis, and poliomyelitis. Data from studies reporting the incidence of diphtheria and pertussis exemplify the shift in epidemiology to older children/adolescents. Seroprevalence data suggest that immunity to pertussis and diphtheria is below the level of herd immunity in several Asian countries in this population. Conclusion: The true burden of diphtheria, pertussis, and tetanus in children aged 3-18 years in Asia is unknown because of weak or absent nationwide surveillance systems. The available evidence highlights the inadequacies in immunity, either by gaps in a recommendation or suboptimal booster coverage, supporting the public health need for booster vaccinations in this population.http://www.sciencedirect.com/science/article/pii/S1201971222000534Public HealthPolicyDiphtheriaPertussisPoliovirusTetanus |
| spellingShingle | Lindsay Nicholson Elizabeth Adkins Mulya Rahma Karyanti Anna Ong-Lim Bhaskar Shenoy Catherine Huoi Juan C. Vargas-Zambrano What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. International Journal of Infectious Diseases Public Health Policy Diphtheria Pertussis Poliovirus Tetanus |
| title | What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. |
| title_full | What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. |
| title_fullStr | What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. |
| title_full_unstemmed | What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. |
| title_short | What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review. |
| title_sort | what is the true burden of diphtheria tetanus pertussis and poliovirus in children aged 3 18 years in asia a systematic literature review |
| topic | Public Health Policy Diphtheria Pertussis Poliovirus Tetanus |
| url | http://www.sciencedirect.com/science/article/pii/S1201971222000534 |
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