Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing

Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing

Fentanyl elicits profound disturbances in ventilatory control processes in humans and experimental animals. The traditional viewpoint with respect to fentanyl-induced respiratory depression is that once the effects on the frequency of breathing (Freq), tidal volume (TV), and minute ventilation (MV =...

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Autors principals: Santhosh M. Baby, Walter J. May, Paulina M. Getsy, Gregory A. Coffee, Tej Nakashe, James N. Bates, Alan Levine, Stephen J. Lewis
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2024-04-01
Col·lecció:Frontiers in Pharmacology
Matèries:
fentanyl
breathing
opioid receptors
naloxone methiodide
rats
Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2024.1381073/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1381073/full

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