Alginate-Based Materials Loaded with Nanoparticles in Wound Healing
Alginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. N...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-04-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/15/4/1142 |
| _version_ | 1797603857779392512 |
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| author | Anna Froelich Emilia Jakubowska Monika Wojtyłko Barbara Jadach Michał Gackowski Piotr Gadziński Olga Napierała Yulia Ravliv Tomasz Osmałek |
| author_facet | Anna Froelich Emilia Jakubowska Monika Wojtyłko Barbara Jadach Michał Gackowski Piotr Gadziński Olga Napierała Yulia Ravliv Tomasz Osmałek |
| author_sort | Anna Froelich |
| collection | DOAJ |
| description | Alginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. Numerous studies indicate that alginate applied in wound care can be enhanced with the incorporation of nanoparticles, revealing additional properties beneficial in the healing process. Among the most extensively explored materials, composite dressings with alginate loaded with antimicrobial inorganic nanoparticles can be mentioned. However, other types of nanoparticles with antibiotics, growth factors, and other active ingredients are also investigated. This review article focuses on the most recent findings regarding novel alginate-based materials loaded with nanoparticles and their applicability as wound dressings, with special attention paid to the materials of potential use in the treatment of chronic wounds. |
| first_indexed | 2024-03-11T04:37:57Z |
| format | Article |
| id | doaj.art-18e8d0d5cfe240ba9ac08d4d480a56f6 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-11T04:37:57Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-18e8d0d5cfe240ba9ac08d4d480a56f62023-11-17T20:53:19ZengMDPI AGPharmaceutics1999-49232023-04-01154114210.3390/pharmaceutics15041142Alginate-Based Materials Loaded with Nanoparticles in Wound HealingAnna Froelich0Emilia Jakubowska1Monika Wojtyłko2Barbara Jadach3Michał Gackowski4Piotr Gadziński5Olga Napierała6Yulia Ravliv7Tomasz Osmałek8Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandDepartment of Pharmacy Management, Economics and Technology, I. Horbachevsky Ternopil National Medical University, 36 Ruska Street, 46000 Ternopil, UkraineChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznań, PolandAlginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. Numerous studies indicate that alginate applied in wound care can be enhanced with the incorporation of nanoparticles, revealing additional properties beneficial in the healing process. Among the most extensively explored materials, composite dressings with alginate loaded with antimicrobial inorganic nanoparticles can be mentioned. However, other types of nanoparticles with antibiotics, growth factors, and other active ingredients are also investigated. This review article focuses on the most recent findings regarding novel alginate-based materials loaded with nanoparticles and their applicability as wound dressings, with special attention paid to the materials of potential use in the treatment of chronic wounds.https://www.mdpi.com/1999-4923/15/4/1142woundalginatenanoparticleshealingwound dressings |
| spellingShingle | Anna Froelich Emilia Jakubowska Monika Wojtyłko Barbara Jadach Michał Gackowski Piotr Gadziński Olga Napierała Yulia Ravliv Tomasz Osmałek Alginate-Based Materials Loaded with Nanoparticles in Wound Healing Pharmaceutics wound alginate nanoparticles healing wound dressings |
| title | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
| title_full | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
| title_fullStr | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
| title_full_unstemmed | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
| title_short | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
| title_sort | alginate based materials loaded with nanoparticles in wound healing |
| topic | wound alginate nanoparticles healing wound dressings |
| url | https://www.mdpi.com/1999-4923/15/4/1142 |
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