Effect of Surface Roughness on Aggregation of Polypeptide Chains: A Monte Carlo Study

Effect of Surface Roughness on Aggregation of Polypeptide Chains: A Monte Carlo Study

The self-assembly of amyloidogenic peptides and proteins into fibrillar structures has been intensively studied for several decades, because it seems to be associated with a number of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease. Therefore, understanding the molecular mech...

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Bibliographic Details
Main Authors:	Nguyen Truong Co, Mai Suan Li
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Biomolecules
Subjects:	protein aggregation aggregation of polypeptide chains fibril formation neurodegenerative diseases surface roughness lattice model
Online Access:	https://www.mdpi.com/2218-273X/11/4/596

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