Regio- and enantioselective remote hydroarylation using a ligand-relay strategy
Migratory alkene isomerizations and cross-coupling reactions are both possible under nickel catalysis, but usually require different conditions. Here the authors show a combined protocol to isomerize a double bond and then, via an in-situ exchange of ligands, perform an enantioselective C(sp2)–C(sp3...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30006-2 |