The role of opportunistic pathogens as etiological agents of intrauterine infections

The study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection. HSV remains the most common etiological agent of intrauterine infections among herpesviruses — markers of active infection ca...

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Bibliographic Details
Main Authors: V. V. Kosenchuk, T. N. Rybalkina, R. E. Boshyan, N. V. Karazhas, M. N. Kornienko, P. A. Veselovsky, M. Yu. Lysenkova, M. S. Savenkova, M. Yu. Ivanova
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2019-10-01
Series:Детские инфекции (Москва)
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Online Access:https://detinf.elpub.ru/jour/article/view/439
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Summary:The study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection. HSV remains the most common etiological agent of intrauterine infections among herpesviruses — markers of active infection caused by this virus were found in 28.3% samples. The difficulty of determining the source of infection in the absence of data in the early stages of pregnancy is presented on 4 out of 10 cases of active HHV-6 infection. Markers of active pneumocystic infection were detected only in mothers: in the group with children under the age of 21 days — in 21—27% of cases, with children aged 22 to 28 days — in 15—21%. In addition to non-specific multiple organ failure during intrauterine infections (26.3%), only one organ system was observed: hypoxic-hemorrhagic lesions of the central nervous system were diagnosed more often — 17%, as well as meningitis/encephalitis, or hepatitis, or pneumonia, or disorders of hematopoiesis, or rash. In 17.5% of children from the comparison group, i.e. without any clinical manifestations of intrauterine infections, markers of active herpes virus infections were detected.
ISSN:2072-8107