The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial
Introduction Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints. Physicians have tried several ways to decrease the pain in these patients. This study aimed to evaluate the effect of...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2022-11-01
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| Series: | Rheumatology |
| Subjects: | |
| Online Access: | https://reu.termedia.pl/The-impact-of-intra-sacroiliac-joint-methylprednisolone-injection-in-the-recovery,150705,0,2.html |
| _version_ | 1797435093533327360 |
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| author | Elham Rajaei Khaled Bavieh Karim Mowla Ali Ghorbani Nooshin Movaffagh |
| author_facet | Elham Rajaei Khaled Bavieh Karim Mowla Ali Ghorbani Nooshin Movaffagh |
| author_sort | Elham Rajaei |
| collection | DOAJ |
| description | Introduction
Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints. Physicians have tried several ways to decrease the pain in these patients. This study aimed to evaluate the effect of intra-sacroiliac joint methylprednisolone injection under the guidance of ultra-
sonography in spondyloarthropathy patients.
Material and methods
In this randomized control trial we studied 60 patients with spondyloarthropathy (30 patients in the intervention group and 30 patients in the control group) from January 2020 to December 2020. The intervention group patients received 40 mg of intra-sacroiliac joint (SIJ) methylprednisolone injection at the beginning in addition to treatment with nonsteroidal
anti-inflammatory drugs (inflammatory dose) and sulfasalazine (2 to 3 g/day). Patients’ pain intensity and symptoms were assessed in the 2nd, 4th, 6th, and 8th weeks after glucocorticosteroid injection. Quantitative factors were compared by independent Student’s t-test. Data analysis was performed using SPSS version 22.0 software. A p-value < 0.005 was considered significant.
Results
There were no statistically significant differences in Visual Analogue Scale (VAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) criteria and finger-to-floor (FTF) levels in the intervention and control groups. There were significant differences in VAS and BASDAI criteria and FTF levels 2 weeks after the injection, and this difference remained the same until the end of the 8th week. The p-value was significant (p-value < 0.0001).
Conclusions
The sacroiliac joint methylprednisolone injection approach with ultrasound guidance seems to be effective in pain relief and function, and patient satisfaction scores. Additionally using the guidance of ultrasonography in this approach is without the risk of radiation exposure. |
| first_indexed | 2024-03-09T10:43:12Z |
| format | Article |
| id | doaj.art-18f31625d7fb4a6fb4e3dd831c61f5ae |
| institution | Directory Open Access Journal |
| issn | 0034-6233 2084-9834 |
| language | English |
| last_indexed | 2024-03-09T10:43:12Z |
| publishDate | 2022-11-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj.art-18f31625d7fb4a6fb4e3dd831c61f5ae2023-12-01T12:16:21ZengTermedia Publishing HouseRheumatology0034-62332084-98342022-11-0160533233910.5114/reum.2022.120285150705The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trialElham Rajaei0Khaled Bavieh1Karim Mowla2Ali Ghorbani3Nooshin Movaffagh4Clinical Research Development Unit, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, IranClinical Research Development Unit, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, IranClinical Research Development Unit, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, IranChronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, IranClinical Research Development Unit, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, IranIntroduction Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints. Physicians have tried several ways to decrease the pain in these patients. This study aimed to evaluate the effect of intra-sacroiliac joint methylprednisolone injection under the guidance of ultra- sonography in spondyloarthropathy patients. Material and methods In this randomized control trial we studied 60 patients with spondyloarthropathy (30 patients in the intervention group and 30 patients in the control group) from January 2020 to December 2020. The intervention group patients received 40 mg of intra-sacroiliac joint (SIJ) methylprednisolone injection at the beginning in addition to treatment with nonsteroidal anti-inflammatory drugs (inflammatory dose) and sulfasalazine (2 to 3 g/day). Patients’ pain intensity and symptoms were assessed in the 2nd, 4th, 6th, and 8th weeks after glucocorticosteroid injection. Quantitative factors were compared by independent Student’s t-test. Data analysis was performed using SPSS version 22.0 software. A p-value < 0.005 was considered significant. Results There were no statistically significant differences in Visual Analogue Scale (VAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) criteria and finger-to-floor (FTF) levels in the intervention and control groups. There were significant differences in VAS and BASDAI criteria and FTF levels 2 weeks after the injection, and this difference remained the same until the end of the 8th week. The p-value was significant (p-value < 0.0001). Conclusions The sacroiliac joint methylprednisolone injection approach with ultrasound guidance seems to be effective in pain relief and function, and patient satisfaction scores. Additionally using the guidance of ultrasonography in this approach is without the risk of radiation exposure.https://reu.termedia.pl/The-impact-of-intra-sacroiliac-joint-methylprednisolone-injection-in-the-recovery,150705,0,2.htmlultrasonographymethylprednisolonespondyloarthropathiessacroiliac joint |
| spellingShingle | Elham Rajaei Khaled Bavieh Karim Mowla Ali Ghorbani Nooshin Movaffagh The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial Rheumatology ultrasonography methylprednisolone spondyloarthropathies sacroiliac joint |
| title | The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial |
| title_full | The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial |
| title_fullStr | The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial |
| title_full_unstemmed | The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial |
| title_short | The impact of intra-sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy: a randomized controlled trial |
| title_sort | impact of intra sacroiliac joint methylprednisolone injection in the recovery of patients with spondyloarthropathy a randomized controlled trial |
| topic | ultrasonography methylprednisolone spondyloarthropathies sacroiliac joint |
| url | https://reu.termedia.pl/The-impact-of-intra-sacroiliac-joint-methylprednisolone-injection-in-the-recovery,150705,0,2.html |
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