Characterization of Human Herpesvirus 8 genomic integration and amplification events in a primary effusion lymphoma cell line

Characterization of Human Herpesvirus 8 genomic integration and amplification events in a primary effusion lymphoma cell line

In this study, we investigated the integration of Human Herpesvirus 8 (HHV-8) into the human genome using the primary effusion lymphoma (PEL) cell line BC-3. Through next-generation sequencing (NGS) data from multiple independent sequencing runs, we identified two highly supported HHV-8 integrants....

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Bibliographic Details
Main Authors: Eva G. Álvarez, Paula Otero, Bernardo Rodríguez-Martín, Ana Pequeño-Valtierra, Iago Otero, André Vidal-Capón, Jorge Rodríguez-Castro, Juan J. Pasantes, Carmen Rivas, Jose M.C. Tubío, Daniel García-Souto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Virology
Subjects:
HHV-8
extrachromosomal chimeric circular DNA
primary effusion lymphoma
long-read sequencing
cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2023.1253416/full

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