Identification of microRNAs linked to regulators of muscle protein synthesis and regeneration in young and old skeletal muscle.
BACKGROUND: Over the course of ageing there is a natural and progressive loss of skeletal muscle mass. The onset and progression of age-related muscle wasting is associated with an attenuated activation of Akt-mTOR signalling and muscle protein synthesis in response to anabolic stimuli such as resis...
Main Authors: | Evelyn Zacharewicz, Paul Della Gatta, John Reynolds, Andrew Garnham, Tamsyn Crowley, Aaron P Russell, Séverine Lamon |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4252069?pdf=render |
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