Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia
Background: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem. Objectives: The purpose of this study was to determine the antibiotic resis...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine
2016-06-01
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| Series: | JKKI (Jurnal Kedokteran dan Kesehatan Indonesia) |
| Subjects: | |
| Online Access: | https://journal.uii.ac.id/JKKI/article/view/5058 |
| Summary: | Background: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem.
Objectives: The purpose of this study was to determine the antibiotic resistance patterns of several diarrhea-causing enteric bacteria that are frequently found in Indonesia, particularly Salmonella, Shigella and Vibrio.
Methods: A cross-sectional study was conducted , among 150 rectal swabs collected from patients with diarrhea, the enteric pathogens isolated comprised Shigella (11.4%), Salmonella (6.6%) and Vibrio(2.7%).
Results: Antibiotic susceptibility test on Shigella species to several antibiotics such as ampicillin, chloramphenicol, tetracycline and, trimethoprim-sulfamethoxazole showed a considerably high resistance rate (25%-100%), whereas ceftriaxone, ciprofloxacin, norfloxacin and nalidixic acid were apparently still effective (resistance rate 0%). Non-typhoid Salmonella had similar resistance patterns as those of Shigella, particularly to ampicillin, tetracycline, chloramphenicol and trimethoprim- sulfamethoxazole However, for S. typhi it was found that all antibiotics were still effective. Vibrio was resistant to ampicillin (resistance rate 100%), whereas the other antibiotics were still effective. Conclusion: It may be concluded that for each of the enteric pathogens the antibiotic resistance pattern should be determined. Use of antibiotics should be based on the antibiotic susceptibility tests. |
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| ISSN: | 2085-4145 2527-2950 |