Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia
Background: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem. Objectives: The purpose of this study was to determine the antibiotic resis...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine
2016-06-01
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| Series: | JKKI (Jurnal Kedokteran dan Kesehatan Indonesia) |
| Subjects: | |
| Online Access: | https://journal.uii.ac.id/JKKI/article/view/5058 |
| _version_ | 1828517742542585856 |
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| author | Meiyanti Meiyanti Oktavianus Ch Salim Elly Herwana Joice V kalumpiu Murad Lesmana |
| author_facet | Meiyanti Meiyanti Oktavianus Ch Salim Elly Herwana Joice V kalumpiu Murad Lesmana |
| author_sort | Meiyanti Meiyanti |
| collection | DOAJ |
| description | Background: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem.
Objectives: The purpose of this study was to determine the antibiotic resistance patterns of several diarrhea-causing enteric bacteria that are frequently found in Indonesia, particularly Salmonella, Shigella and Vibrio.
Methods: A cross-sectional study was conducted , among 150 rectal swabs collected from patients with diarrhea, the enteric pathogens isolated comprised Shigella (11.4%), Salmonella (6.6%) and Vibrio(2.7%).
Results: Antibiotic susceptibility test on Shigella species to several antibiotics such as ampicillin, chloramphenicol, tetracycline and, trimethoprim-sulfamethoxazole showed a considerably high resistance rate (25%-100%), whereas ceftriaxone, ciprofloxacin, norfloxacin and nalidixic acid were apparently still effective (resistance rate 0%). Non-typhoid Salmonella had similar resistance patterns as those of Shigella, particularly to ampicillin, tetracycline, chloramphenicol and trimethoprim- sulfamethoxazole However, for S. typhi it was found that all antibiotics were still effective. Vibrio was resistant to ampicillin (resistance rate 100%), whereas the other antibiotics were still effective. Conclusion: It may be concluded that for each of the enteric pathogens the antibiotic resistance pattern should be determined. Use of antibiotics should be based on the antibiotic susceptibility tests. |
| first_indexed | 2024-12-11T18:44:44Z |
| format | Article |
| id | doaj.art-18fd7f84c7894d069247defc68494503 |
| institution | Directory Open Access Journal |
| issn | 2085-4145 2527-2950 |
| language | English |
| last_indexed | 2024-12-11T18:44:44Z |
| publishDate | 2016-06-01 |
| publisher | Faculty of Medicine |
| record_format | Article |
| series | JKKI (Jurnal Kedokteran dan Kesehatan Indonesia) |
| spelling | doaj.art-18fd7f84c7894d069247defc684945032022-12-22T00:54:29ZengFaculty of MedicineJKKI (Jurnal Kedokteran dan Kesehatan Indonesia)2085-41452527-29502016-06-01739510110.20885/JKKI.Vol7.Iss3.art44518Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, IndonesiaMeiyanti Meiyanti0Oktavianus Ch Salim1Elly Herwana2Joice V kalumpiu3Murad Lesmana4Department of Pharmacology, Faculty of Medicine, Trisakti UniversityDepartment of Public Health, Faculty of Medicine, Trisakti UniversityDepartment of Pharmacology, Faculty of Medicine, Trisakti UniversityDepartment of Pharmacology, Faculty of Medicine, Trisakti UniversityDepartment of Microbiology, Faculty of Medicine, Trisakti UniversityBackground: The rapid increase of antibiotic resistance among enteric pathogens in developing countries has become a great concern. In Indonesia, Salmonella, Shigella, and Vibro are still an important public health problem. Objectives: The purpose of this study was to determine the antibiotic resistance patterns of several diarrhea-causing enteric bacteria that are frequently found in Indonesia, particularly Salmonella, Shigella and Vibrio. Methods: A cross-sectional study was conducted , among 150 rectal swabs collected from patients with diarrhea, the enteric pathogens isolated comprised Shigella (11.4%), Salmonella (6.6%) and Vibrio(2.7%). Results: Antibiotic susceptibility test on Shigella species to several antibiotics such as ampicillin, chloramphenicol, tetracycline and, trimethoprim-sulfamethoxazole showed a considerably high resistance rate (25%-100%), whereas ceftriaxone, ciprofloxacin, norfloxacin and nalidixic acid were apparently still effective (resistance rate 0%). Non-typhoid Salmonella had similar resistance patterns as those of Shigella, particularly to ampicillin, tetracycline, chloramphenicol and trimethoprim- sulfamethoxazole However, for S. typhi it was found that all antibiotics were still effective. Vibrio was resistant to ampicillin (resistance rate 100%), whereas the other antibiotics were still effective. Conclusion: It may be concluded that for each of the enteric pathogens the antibiotic resistance pattern should be determined. Use of antibiotics should be based on the antibiotic susceptibility tests.https://journal.uii.ac.id/JKKI/article/view/5058antibiotic resistance , diarrhea patient, Jakarta |
| spellingShingle | Meiyanti Meiyanti Oktavianus Ch Salim Elly Herwana Joice V kalumpiu Murad Lesmana Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia JKKI (Jurnal Kedokteran dan Kesehatan Indonesia) antibiotic resistance , diarrhea patient, Jakarta |
| title | Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia |
| title_full | Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia |
| title_fullStr | Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia |
| title_full_unstemmed | Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia |
| title_short | Antibiotic susceptibility of Salmonella, Shigella and Vibrio isolated from diarrhea patients in Jakarta, Indonesia |
| title_sort | antibiotic susceptibility of salmonella shigella and vibrio isolated from diarrhea patients in jakarta indonesia |
| topic | antibiotic resistance , diarrhea patient, Jakarta |
| url | https://journal.uii.ac.id/JKKI/article/view/5058 |
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