The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers
There is growing concern among healthcare providers worldwide regarding the prevalence of multidrug-resistant <i>Acinetobacter baumannii</i> (<i>A. baumannii</i>). Some of the worst hospital-acquired infections, often in intensive care units (ICUs), are caused by this bacteri...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/11/7/1171 |
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| author | Ayman Elbehiry Eman Marzouk Ihab Moussa Yazeed Mushayt Ahmad Abdullah Algarni Osama Ali Alrashed Khalid Saad Alghamdi Naif Ahmed Almutairi Sulaiman Abdulaziz Anagreyyah Anwar Alzahrani Abdulaziz M. Almuzaini Feras Alzaben Meshal Abdullah Alotaibi Suha Abdulaziz Anjiria Akram Abu-Okail Adil Abalkhail |
| author_facet | Ayman Elbehiry Eman Marzouk Ihab Moussa Yazeed Mushayt Ahmad Abdullah Algarni Osama Ali Alrashed Khalid Saad Alghamdi Naif Ahmed Almutairi Sulaiman Abdulaziz Anagreyyah Anwar Alzahrani Abdulaziz M. Almuzaini Feras Alzaben Meshal Abdullah Alotaibi Suha Abdulaziz Anjiria Akram Abu-Okail Adil Abalkhail |
| author_sort | Ayman Elbehiry |
| collection | DOAJ |
| description | There is growing concern among healthcare providers worldwide regarding the prevalence of multidrug-resistant <i>Acinetobacter baumannii</i> (<i>A. baumannii</i>). Some of the worst hospital-acquired infections, often in intensive care units (ICUs), are caused by this bacterial pathogen. In recent years, the rise in multidrug-resistant <i>A. baumannii</i> has been linked to the overuse of antimicrobial drugs and the lack of adequate infection control measures. Infections caused by this bacterial pathogen are the result of prolonged hospitalization and ICU stays, and they are associated with increased morbidity and mortality. This review outlines the epidemiology, risk factors, and antimicrobial resistance associated with <i>A. baumannii</i> in various countries, with a special focus on the Kingdom of Saudi Arabia. In response to the growing concern regarding this drug-resistant bacteria, fundamental information about its pathology has been incorporated into the development of vaccines. Although these vaccines have been successful in animal models, their effectiveness in humans remains unproven. The review will discuss the development of <i>A. baumannii</i> vaccines, potential related obstacles, and efforts to find an effective strategy against this pathogen. |
| first_indexed | 2024-03-11T00:34:54Z |
| format | Article |
| id | doaj.art-18ff93d7c45b4ac2b8a9cfecd03090fc |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-11T00:34:54Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-18ff93d7c45b4ac2b8a9cfecd03090fc2023-11-18T21:40:37ZengMDPI AGVaccines2076-393X2023-06-01117117110.3390/vaccines11071171The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare ProvidersAyman Elbehiry0Eman Marzouk1Ihab Moussa2Yazeed Mushayt3Ahmad Abdullah Algarni4Osama Ali Alrashed5Khalid Saad Alghamdi6Naif Ahmed Almutairi7Sulaiman Abdulaziz Anagreyyah8Anwar Alzahrani9Abdulaziz M. Almuzaini10Feras Alzaben11Meshal Abdullah Alotaibi12Suha Abdulaziz Anjiria13Akram Abu-Okail14Adil Abalkhail15Department of Public Health, College of Public Health and Health Informatics, Qassim University, Al Bukayriyah 52741, Saudi ArabiaDepartment of Public Health, College of Public Health and Health Informatics, Qassim University, Al Bukayriyah 52741, Saudi ArabiaDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Support Service, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaFamily Medicine Department, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaFamily Medicine Department, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaFamily Medicine Department, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaFamily Medicine Department, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaFamily Medicine Department, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaCardiac Center, King Fahad Armed Forces Hospital, Jeddah 23311, Saudi ArabiaDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraydah 52571, Saudi ArabiaDepartment of Food Service, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaAcademic Affairs, King Fahad Armed Hospital, Jeddah 23311, Saudi ArabiaPharmacy Department, King Abdullah Medical Complex, Jeddah 23816, Saudi ArabiaDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraydah 52571, Saudi ArabiaDepartment of Public Health, College of Public Health and Health Informatics, Qassim University, Al Bukayriyah 52741, Saudi ArabiaThere is growing concern among healthcare providers worldwide regarding the prevalence of multidrug-resistant <i>Acinetobacter baumannii</i> (<i>A. baumannii</i>). Some of the worst hospital-acquired infections, often in intensive care units (ICUs), are caused by this bacterial pathogen. In recent years, the rise in multidrug-resistant <i>A. baumannii</i> has been linked to the overuse of antimicrobial drugs and the lack of adequate infection control measures. Infections caused by this bacterial pathogen are the result of prolonged hospitalization and ICU stays, and they are associated with increased morbidity and mortality. This review outlines the epidemiology, risk factors, and antimicrobial resistance associated with <i>A. baumannii</i> in various countries, with a special focus on the Kingdom of Saudi Arabia. In response to the growing concern regarding this drug-resistant bacteria, fundamental information about its pathology has been incorporated into the development of vaccines. Although these vaccines have been successful in animal models, their effectiveness in humans remains unproven. The review will discuss the development of <i>A. baumannii</i> vaccines, potential related obstacles, and efforts to find an effective strategy against this pathogen.https://www.mdpi.com/2076-393X/11/7/1171multidrug-resistant <i>Acinetobacter baumannii</i>prevalencehealthcare settingsvaccination strategies |
| spellingShingle | Ayman Elbehiry Eman Marzouk Ihab Moussa Yazeed Mushayt Ahmad Abdullah Algarni Osama Ali Alrashed Khalid Saad Alghamdi Naif Ahmed Almutairi Sulaiman Abdulaziz Anagreyyah Anwar Alzahrani Abdulaziz M. Almuzaini Feras Alzaben Meshal Abdullah Alotaibi Suha Abdulaziz Anjiria Akram Abu-Okail Adil Abalkhail The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers Vaccines multidrug-resistant <i>Acinetobacter baumannii</i> prevalence healthcare settings vaccination strategies |
| title | The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers |
| title_full | The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers |
| title_fullStr | The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers |
| title_full_unstemmed | The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers |
| title_short | The Prevalence of Multidrug-Resistant <i>Acinetobacter baumannii</i> and Its Vaccination Status among Healthcare Providers |
| title_sort | prevalence of multidrug resistant i acinetobacter baumannii i and its vaccination status among healthcare providers |
| topic | multidrug-resistant <i>Acinetobacter baumannii</i> prevalence healthcare settings vaccination strategies |
| url | https://www.mdpi.com/2076-393X/11/7/1171 |
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