Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

Background:. Although radiation therapy remains an integral component in cancer treatment, the sequela of tissue damage can result in long-term morbidity and mortality for patients. This article aimed to perform a comprehensive review of the current literature for both nonsurgical and surgical manag...

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Bibliographic Details
Main Authors: Richard Simman, MD, FACS, FACCWS, Karen Bach, BS, Fuad Abbas, BS, Kara Klomparens, BS, Bradley Joseph Brickman, BS
Format: Article
Language:English
Published: Wolters Kluwer 2023-06-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005043
Description
Summary:Background:. Although radiation therapy remains an integral component in cancer treatment, the sequela of tissue damage can result in long-term morbidity and mortality for patients. This article aimed to perform a comprehensive review of the current literature for both nonsurgical and surgical management strategies for radiation-induced injuries. Methods:. A literature search was performed on PubMed to review the current described management and treatment options for radiation-induced injuries. Patient demographics, medical diagnoses, complications, strategies of management care, and outcomes were reviewed. Results:. The most commonly described management options and reconstructive techniques of radiation wounds were analyzed and reported. Conclusions:. Consideration of current techniques and outcomes in the management of radiation-induced wounds demonstrates that impaired wound healing remains a major problem. This literature review provides a detailed overview of the most frequently used therapies with recommendations for surgeons.
ISSN:2169-7574