Protective action of deferiprone and deferoxamine in erythrocytes isolated from patients with β-thalassemias

Protective action of deferiprone and deferoxamine in erythrocytes isolated from patients with β-thalassemias

One of the most deleterious consequences of iron overload in thalassemia is the presence of non-transferrin bound iron (NTBI), a free radical that acts as a catalyst for free oxygen radicals, in particular for hydroxyl free radicals (OH.). These radicals oxidize both membrane lipids and proteins cau...

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Bibliographic Details
Main Authors:	Alisson F. Santos, Giorgio Baldanzi, Maria Suely S. Leonart, Aguinaldo J. Nascimento
Format:	Article
Language:	English
Published:	Elsevier 2009-01-01
Series:	Revista Brasileira de Hematologia e Hemoterapia
Subjects:	Quelantes de ferro desferoxamina deferiprona eritrócitos
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000600013&lng=en&tlng=en

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