Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators

Abstract Photoacoustic (PA) imaging enables noninvasive volumetric imaging of biological tissues by capturing the endogenous optical absorption contrast. Conventional ultrasound detectors using piezoelectric materials have been widely used for transducing ultrasound signals into the electrical signa...

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Main Authors: Youngseop Lee, Hao F. Zhang, Cheng Sun
Format: Article
Language:English
Published: SpringerOpen 2023-06-01
Series:Nano Convergence
Subjects:
Online Access:https://doi.org/10.1186/s40580-023-00378-2
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author Youngseop Lee
Hao F. Zhang
Cheng Sun
author_facet Youngseop Lee
Hao F. Zhang
Cheng Sun
author_sort Youngseop Lee
collection DOAJ
description Abstract Photoacoustic (PA) imaging enables noninvasive volumetric imaging of biological tissues by capturing the endogenous optical absorption contrast. Conventional ultrasound detectors using piezoelectric materials have been widely used for transducing ultrasound signals into the electrical signals for PA imaging reconstruction. However, their inherent limitations in detection bandwidth and sensitivity per unit area have unfortunately constrained the performance of PA imaging. Optical based ultrasound detection methods emerge to offer very promising solutions. In particular, polymer micro-ring resonators (MRRs) in the form of integrated photonic circuits (IPC) enable significant reduction for the sensing area to 80 μm in diameter, while maintaining highly sensitive ultrasound detection with noise equivalent pressure (NEP) of 0.49 Pa and a broad detection frequency range up to 250 MHz. The continued engineering innovation has further transformed MRRs to be transparent to the light and thus, opens up a wide range of applications, including multi-modality optical microscope with isometric resolution, PA endoscope, photoacoustic computed tomography (PACT), and more. This review article summarizes and discusses the evolution of polymer MRR design and the associated nanofabrication process for improving the performance of ultrasound detection. The resulting novel imaging applications will also be reviewed and discussed.
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spelling doaj.art-1905d77e896d4560b084c56a26e7ef362023-06-25T11:24:44ZengSpringerOpenNano Convergence2196-54042023-06-0110111910.1186/s40580-023-00378-2Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonatorsYoungseop Lee0Hao F. Zhang1Cheng Sun2Department of Biomedical Engineering, Northwestern UniversityDepartment of Biomedical Engineering, Northwestern UniversityDepartment of Mechanical Engineering, Northwestern UniversityAbstract Photoacoustic (PA) imaging enables noninvasive volumetric imaging of biological tissues by capturing the endogenous optical absorption contrast. Conventional ultrasound detectors using piezoelectric materials have been widely used for transducing ultrasound signals into the electrical signals for PA imaging reconstruction. However, their inherent limitations in detection bandwidth and sensitivity per unit area have unfortunately constrained the performance of PA imaging. Optical based ultrasound detection methods emerge to offer very promising solutions. In particular, polymer micro-ring resonators (MRRs) in the form of integrated photonic circuits (IPC) enable significant reduction for the sensing area to 80 μm in diameter, while maintaining highly sensitive ultrasound detection with noise equivalent pressure (NEP) of 0.49 Pa and a broad detection frequency range up to 250 MHz. The continued engineering innovation has further transformed MRRs to be transparent to the light and thus, opens up a wide range of applications, including multi-modality optical microscope with isometric resolution, PA endoscope, photoacoustic computed tomography (PACT), and more. This review article summarizes and discusses the evolution of polymer MRR design and the associated nanofabrication process for improving the performance of ultrasound detection. The resulting novel imaging applications will also be reviewed and discussed.https://doi.org/10.1186/s40580-023-00378-2Photoacoustic imagingMicro-ring resonatorUltrasound detectorNano-fabricationMaskless lithographyNanoimprint lithography
spellingShingle Youngseop Lee
Hao F. Zhang
Cheng Sun
Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
Nano Convergence
Photoacoustic imaging
Micro-ring resonator
Ultrasound detector
Nano-fabrication
Maskless lithography
Nanoimprint lithography
title Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
title_full Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
title_fullStr Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
title_full_unstemmed Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
title_short Highly sensitive ultrasound detection using nanofabricated polymer micro-ring resonators
title_sort highly sensitive ultrasound detection using nanofabricated polymer micro ring resonators
topic Photoacoustic imaging
Micro-ring resonator
Ultrasound detector
Nano-fabrication
Maskless lithography
Nanoimprint lithography
url https://doi.org/10.1186/s40580-023-00378-2
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