Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma

Organs consist of parenchyma and stroma. Nishinakamura and colleagues induce renal stromal progenitors from mouse pluripotent stem cells (PSCs), and generate completely PSC-derived organoids that reproduce complex kidney structure.

Bibliographic Details
Main Authors: Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi, Ryuichi Nishinakamura
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28226-7
Description
Summary:Organs consist of parenchyma and stroma. Nishinakamura and colleagues induce renal stromal progenitors from mouse pluripotent stem cells (PSCs), and generate completely PSC-derived organoids that reproduce complex kidney structure.
ISSN:2041-1723