Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

Cough is induced by inhaled prostacyclin analogues including treprostinil (TRE), and, at higher doses, treprostinil palmitil (TP), a prodrug of TRE. In this report, we have investigated mechanisms involved in TRE- and TP-induced cough, using a dry powder formulation of TP (TPIP) to supplement previo...

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Bibliographic Details
Main Authors: Richard W. Chapman, Michel R. Corboz, Carlos Fernandez, Eugene Sullivan, Andy Stautberg, Adam J. Plaunt, Donna M. Konicek, Vladimir Malinin, Zhili Li, David Cipolla, Walter Perkins
Format: Article
Language:English
Published: European Respiratory Society 2021-02-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/7/1/00592-2020.full

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