Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience
Introduction: Nephrectomy is a common surgical procedure done for a variety of neoplastic and nonneoplastic diseases. This study has been taken up to analyze kidney diseases histopathologically and various lesions of the kidney and their subtypes and record the various lesions which have lead to...
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| Format: | Article |
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JCDR Research and Publications Pvt. Ltd.
2016-04-01
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| Series: | National Journal of Laboratory Medicine |
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| Online Access: | http://www.njlm.net/articles/PDF/2112/11-%2018261_F(P)_PF1(Vsu_Om)_PFA(Om)_PF2(OMVSU).pdf |
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| author | Vikram Narang Bhavna Garg Ashneet Walia Neena Sood Vineeta Malhotra |
| author_facet | Vikram Narang Bhavna Garg Ashneet Walia Neena Sood Vineeta Malhotra |
| author_sort | Vikram Narang |
| collection | DOAJ |
| description | Introduction: Nephrectomy is a common surgical
procedure done for a variety of neoplastic and nonneoplastic diseases. This study has been taken up to
analyze kidney diseases histopathologically and various
lesions of the kidney and their subtypes and record the
various lesions which have lead to partial nephrectomy,
total nephrectomy, unilateral and bilateral nephrectomies.
Aim: To study spectrum of diseases in nephrectomy
specimens, histological sub typing of neoplastic conditions
and evaluation of histopathological prognostic features like
capsular invasion, vascular invasion and nuclear grade.
Materials and Methods: This was an retrospective and
prospective analysis done over the period of 4 years
(2006-2009). A nephrectomy specimens received in the
Department of Pathology Dayanand Medical College and
Hospital, Ludhiana were analyzed with respect to gross
and microscopic features.
Results: Out of a total number of 155 cases, 82 were
neoplastic, 73 were non-neoplastic males were 98
and females 57 with a M:F ratio 1.7:1. Out of the 82
neoplastic cases, Renal cell carcinoma (Clear cell type)
was commonest (57 cases) followed by Transitional
cell carcinoma (07 cases), Papillary RCC (03 cases),
Oncocytoma (03 cases), Wilm’s tumour (02 cases), RCC
with sarcomatoid change (02 cases), RCC unclassifiable
(03 cases) and 01 case each of Chromophobe RCC,
Multicystic RCC, Collecting duct carcinoma and small
round cell tumour respectively. Of the 73 non-neoplastic
cases, chronic pyelonephritis with hydronephrosis
constituted 42 cases, emphysematous pyelonephritis (16
cases), xanthogranulomatous pyelonephritis (02 cases),
acute or chronic pyelonephritis (09 cases), polycystic
kidney (02 cases), cystic renal dysplasia and tuberculosis
(01 case each).
Conclusion: Radical nephrectomy is the common surgical
procedure done for both neoplastic disorders as well as non
neoplastic lesions. Detailed histopathological examination
is necessary for diagnosis and the prognostication of the
lesions. |
| first_indexed | 2024-12-11T22:20:25Z |
| format | Article |
| id | doaj.art-190d2c6ae78046e79884617e8e2d5dc0 |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-12-11T22:20:25Z |
| publishDate | 2016-04-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-190d2c6ae78046e79884617e8e2d5dc02022-12-22T00:48:28ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822016-04-0152515410.7860/NJLM/2016/18261:2112Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience Vikram Narang0 Bhavna Garg1Ashneet Walia2Neena Sood3 Vineeta Malhotra4Assistant Professor, Department of Pathology, Dayanad Medical College and Hospital, Ludhiyana, Punjab, India.Professor, Department of Pathology, Dayanad Medical College and Hospital, Ludhiyana, Punjab, India.Ex Resident, Department of Pathology, Dayanad Medical College and Hospital, Ludhiyana, Punjab, India.Professor and Head, Department of Pathology, Dayanad Medical College and Hospital, Ludhiyana, Punjab, India.Former Professor and Head, Department of Pathology, Dayanad Medical College and Hospital, Ludhiyana, Punjab, India.Introduction: Nephrectomy is a common surgical procedure done for a variety of neoplastic and nonneoplastic diseases. This study has been taken up to analyze kidney diseases histopathologically and various lesions of the kidney and their subtypes and record the various lesions which have lead to partial nephrectomy, total nephrectomy, unilateral and bilateral nephrectomies. Aim: To study spectrum of diseases in nephrectomy specimens, histological sub typing of neoplastic conditions and evaluation of histopathological prognostic features like capsular invasion, vascular invasion and nuclear grade. Materials and Methods: This was an retrospective and prospective analysis done over the period of 4 years (2006-2009). A nephrectomy specimens received in the Department of Pathology Dayanand Medical College and Hospital, Ludhiana were analyzed with respect to gross and microscopic features. Results: Out of a total number of 155 cases, 82 were neoplastic, 73 were non-neoplastic males were 98 and females 57 with a M:F ratio 1.7:1. Out of the 82 neoplastic cases, Renal cell carcinoma (Clear cell type) was commonest (57 cases) followed by Transitional cell carcinoma (07 cases), Papillary RCC (03 cases), Oncocytoma (03 cases), Wilm’s tumour (02 cases), RCC with sarcomatoid change (02 cases), RCC unclassifiable (03 cases) and 01 case each of Chromophobe RCC, Multicystic RCC, Collecting duct carcinoma and small round cell tumour respectively. Of the 73 non-neoplastic cases, chronic pyelonephritis with hydronephrosis constituted 42 cases, emphysematous pyelonephritis (16 cases), xanthogranulomatous pyelonephritis (02 cases), acute or chronic pyelonephritis (09 cases), polycystic kidney (02 cases), cystic renal dysplasia and tuberculosis (01 case each). Conclusion: Radical nephrectomy is the common surgical procedure done for both neoplastic disorders as well as non neoplastic lesions. Detailed histopathological examination is necessary for diagnosis and the prognostication of the lesions.http://www.njlm.net/articles/PDF/2112/11-%2018261_F(P)_PF1(Vsu_Om)_PFA(Om)_PF2(OMVSU).pdfchronic pyelonephritisclear cell renal cell carcinomahistopathologyrenal cell carcinoma |
| spellingShingle | Vikram Narang Bhavna Garg Ashneet Walia Neena Sood Vineeta Malhotra Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience National Journal of Laboratory Medicine chronic pyelonephritis clear cell renal cell carcinoma histopathology renal cell carcinoma |
| title | Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience |
| title_full | Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience |
| title_fullStr | Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience |
| title_full_unstemmed | Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience |
| title_short | Histomorphological Spectrum of Nephrectomy Specimens- A Tertairy Care Centre Experience |
| title_sort | histomorphological spectrum of nephrectomy specimens a tertairy care centre experience |
| topic | chronic pyelonephritis clear cell renal cell carcinoma histopathology renal cell carcinoma |
| url | http://www.njlm.net/articles/PDF/2112/11-%2018261_F(P)_PF1(Vsu_Om)_PFA(Om)_PF2(OMVSU).pdf |
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