Modeling the ACVR1R206H mutation in human skeletal muscle stem cells
Abnormalities in skeletal muscle repair can lead to poor function and complications such as scarring or heterotopic ossification (HO). Here, we use fibrodysplasia ossificans progressiva (FOP), a disease of progressive HO caused by ACVR1R206H (Activin receptor type-1 receptor) mutation, to elucidate...
Main Authors: | Emilie Barruet, Steven M Garcia, Jake Wu, Blanca M Morales, Stanley Tamaki, Tania Moody, Jason H Pomerantz, Edward C Hsiao |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/66107 |
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