Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review
Lung cancer is a highly aggressive neoplasm that is now a leading cause of cancer death worldwide. One of the major approaches for killing cancer cells is related with activation of apoptotic cell death with anti-cancer drugs. However, the efficiency of apoptosis induction in tumors is limited. Cons...
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| Format: | Article |
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MDPI AG
2022-05-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/15/10/3456 |
| _version_ | 1797498236036972544 |
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| author | Joanna Pancewicz Wiesława Ewa Niklińska Adrian Chlanda |
| author_facet | Joanna Pancewicz Wiesława Ewa Niklińska Adrian Chlanda |
| author_sort | Joanna Pancewicz |
| collection | DOAJ |
| description | Lung cancer is a highly aggressive neoplasm that is now a leading cause of cancer death worldwide. One of the major approaches for killing cancer cells is related with activation of apoptotic cell death with anti-cancer drugs. However, the efficiency of apoptosis induction in tumors is limited. Consequently, the development of other forms of non-apoptotic cell death is up to date challenge for scientists worldwide. This situation motivated us to define the aim of this mini-review: gathering knowledge regarding ferroptosis—newly defined programmed cell death process characterized by the excessive accumulation of iron—and combining it with yet another interesting nanomaterial-based graphene approach. In this manuscript, we presented brief information about non-small lung cancer and ferroptosis, followed by a section depicting the key-features of graphene-based nanomaterials influencing their biologically relevant properties. |
| first_indexed | 2024-03-10T03:31:33Z |
| format | Article |
| id | doaj.art-1914cd6181ee44428de0950c6ec79ee4 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T03:31:33Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-1914cd6181ee44428de0950c6ec79ee42023-11-23T11:55:39ZengMDPI AGMaterials1996-19442022-05-011510345610.3390/ma15103456Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini ReviewJoanna Pancewicz0Wiesława Ewa Niklińska1Adrian Chlanda2Department of Histology and Embryology, Medical University in Bialystok, Waszyngtona 13, 15-269 Białystok, PolandDepartment of Histology and Embryology, Medical University in Bialystok, Waszyngtona 13, 15-269 Białystok, PolandGraphene and Composites Research Group, Łukasiewicz Research Network—Institute of Microelectronics and Photonics, al. Lotników 32/46, 02-668 Warszawa, PolandLung cancer is a highly aggressive neoplasm that is now a leading cause of cancer death worldwide. One of the major approaches for killing cancer cells is related with activation of apoptotic cell death with anti-cancer drugs. However, the efficiency of apoptosis induction in tumors is limited. Consequently, the development of other forms of non-apoptotic cell death is up to date challenge for scientists worldwide. This situation motivated us to define the aim of this mini-review: gathering knowledge regarding ferroptosis—newly defined programmed cell death process characterized by the excessive accumulation of iron—and combining it with yet another interesting nanomaterial-based graphene approach. In this manuscript, we presented brief information about non-small lung cancer and ferroptosis, followed by a section depicting the key-features of graphene-based nanomaterials influencing their biologically relevant properties.https://www.mdpi.com/1996-1944/15/10/3456flake graphenegraphene oxideferroptosisnon-small lung cancernanomaterials |
| spellingShingle | Joanna Pancewicz Wiesława Ewa Niklińska Adrian Chlanda Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review Materials flake graphene graphene oxide ferroptosis non-small lung cancer nanomaterials |
| title | Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review |
| title_full | Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review |
| title_fullStr | Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review |
| title_full_unstemmed | Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review |
| title_short | Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review |
| title_sort | flake graphene based nanomaterial approach for triggering a ferroptosis as an attractive theranostic outlook for tackling non small lung cancer a mini review |
| topic | flake graphene graphene oxide ferroptosis non-small lung cancer nanomaterials |
| url | https://www.mdpi.com/1996-1944/15/10/3456 |
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